Colorectal cancer is expected to claim more than 52,000 American lives in 2022, and if this year is like most others, Black Americans will bear the brunt of the disease. To understand the disparity in context, University of Illinois researchers looked at the intersection of bile acids, gut microbes, racial identity, and neighborhood food environment in the development of colorectal cancer.

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so.

As the owner of a human body, you’re carrying trillions of microbes with you everywhere you go. These microscopic organisms aren’t just hitching a ride; many of them perform essential chemical reactions that regulate everything from our digestion to our immune system to our moods.

The human gut consists of a complex community of microbes that consume and secrete hundreds of small molecules—a phenomenon called cross-feeding. However, it is challenging to study these processes experimentally. A new study, published in Nature Communications, uses models to predict cross-feeding interactions between microbial species in the gut. Predictions from such computational methods could eventually help doctors get a more complete understanding of gut health.

Dietary fiber found in grains is a large component of many diets, but little is understood about how we digest the fiber, as humans lack enzymes to break down the complex molecules. Some species of gut bacteria break down the fiber in such a way that it not only becomes digestible, but releases ferulic acid, an important antioxidant with multiple health benefits, according to a new study led by researchers at the University of Illinois Urbana-Champaign.

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants. In a new paper, scientists from Illinois review the research linking dozens of environmental chemicals to changes in the gut microbiome and associated health challenges.

The review is published in the journal Toxicological Sciences.

Microbial communities can be found everywhere – from lakes to the soil on the ground, they are omnipresent yet invisible to the naked eye. Within those environments there exist dynamic communities which fluctuate in response to environmental changes. One such example is the human gut microbiome, which is comprised of microbes that influence the overall landscape of the gut.