Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing — the production of fuels, plastics, and valuable chemicals from plants or other biological systems.

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, dubbed CLEAN, outperforms the leading state-of-the-art tools in accuracy, reliability and sensitivity. Better understanding of enzymes and their functions would be a boon for research in genomics, chemistry, industrial materials, medicine, pharmaceuticals and more.

An unexpected discovery has given scientists a greater understanding of an important methane-producing enzyme.

A team of IGB researchers published a paper in eLife that outlined their findings on an enzyme called methyl-coenzyme M reductase, or MCR.

Their findings overturn what was previously believed to be true in the field: that a set of unique modifications present in MCR were essential to how the enzyme functions.