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Art of Science Gallery 01

aos_01_07
Cellular light switch

Zeiss LSM 700 Confocal Microscope



Image provided by Vladimer Kolossov and Matthew Leslie, Rex Gaskins Lab



Research funded by the National Institutes of Health



The glow seen inside these cells is produced by a biosensor that responds to oxidation state. Cells were genetically engineered to produce the sensor, allowing researchers to track how various environmental conditions, including oxidative stress, affect different parts of the cell.