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Carl R. Woese Institute for Genomic Biology

Where Science Meets Society

Gallery

aos05_11
Battle Testing
Zeiss Lightsheet Z.1; Imaris 3D Visualization Package

Sara Pedron and Bhushan Mahadik
Brendan Harley Laboratory

Funded by the NSF, NIH, and Mayo Clinic-University of Illinois Alliance

The small drops seen in this image are living cancer cells seeded within a hydrogel composed of gelatin and a gradated concentration of hyaluronic acid. Cells are treated with a current anti-cancer drug and their response is tested by counting cells that are alive (colored green) and those that are dead (colored red). Patients with glioblastoma multiforme, the most aggressive form of primary brain tumor, have a very poor prognosis. Tests of anti-cancer drugs in setups that replicate the tumor microenvironment are a critical tool in cancer research.