Infection Genomics for One Health

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Infection Genomics for One Health

The concept of One Health recognizes the fundamental dependence of human health on the health of agricultural, industrial, and natural ecosystems. Microbes form hidden linkages that connect these ecosystems and shape their health and disease. Informed strategies to address urgent and critical threats to human health such as emerging infectious disease, epidemic outbreaks, antimicrobial resistance, and the maintenance of healthy microbial communities require the development of predictive models for the movement of genes, genomes, and microbes among these interconnected microbial ecosystems. Our aim is to develop a broad and predictive framework for infection biology that will directly address these challenges.