Omics Nanotechnology for Cancer Precision Medicine

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Omics Nanotechnology for Cancer Precision Medicine

Thanks to advances in biotech instrumentation and techniques over the last decade, many new molecular targets for cancer treatment have been identified. Nonetheless, selecting optimal therapeutic regimens remains challenging. Often, there are many therapies that can slow disease progression, but they work only for some patients. Moreover, tumors can develop mutations that allow them to evade the treatment. There are no reliable predictive factors, and performing a biopsy on a tumor is invasive and expensive.

ONC-PM researchers work on non-invasive genomic “liquid biopsies” to define disease outcomes and identify the appropriate treatment. These tests look at molecules, known as micro-RNAs (miRNAs) that tumors shed in the blood of cancer patients. The goal is to develop at-home sample collection assays that can be used to identify sub-classes of cancer and to track treatment progress.