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Carl R. Woese Institute for Genomic Biology

Where Science Meets Society

A New Tool for Genetically Engineering the Oldest Branch of Life

A new study by G. William Arends Professor of Microbiology Bill Metcalf and IGB Fellow Dipti Nayak has documented the use of CRISPR-Cas9 mediated genome editing in the third domain of life, Archaea, for the first time. Their groundbreaking work, reported in Proceedings of the National Academy of Sciences [DOI:10.1073/pnas.1618596114], has the potential to vastly accelerate future studies of these organisms, with implications for research including global climate change.

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