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Bringing cells to life … and to Minecraft: $30M NSF grant to support whole-cell modeling

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Researchers, policymakers, and Minecraft players can look forward to the a new research center.

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New Minflux microscope improves molecule tracking in live cells

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Over the past century, our understanding of cells—the basic building blocks of living organisms—has progressed largely due to microscopes. The invention of fluorescence microscopy has been a primary tool in this scientific endeavor because it allows researchers to color-label specific cellular components and observe them in live cells. The new two-color 3-D Minflux microscope is a vast improvement on traditional fluorescence microscopy because, for the first time, researchers can track how two molecules can interact with each other on the size scale of the molecules themselves.

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Computational human cell reveals new insights

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Researchers have developed the first computational model of a human cell and simulated its behavior for 15 minutes – the longest time achieved for a biological system of this complexity. In a new study, simulations reveal the effects of spatial organization within cells on some of the genetic processes that control the regulation and development of human traits and some human diseases.

The study, which produced a new computational platform that is available to any researcher, is published in the journal PLoS Computational Biology.

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