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Scientists test nanoparticle drug delivery in dogs with osteosarcoma

July 25, 2016

At the University of Illinois, an engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. They chose dogs – mammals closer in size and biology to humans – with naturally occurring bone cancers, which also are a lot like human bone tumors.


July 25, 2016


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Shape of tumor may affect whether cells can metastasize

April 28, 2016

Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study.


April 28, 2016


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Cancer and Companion Animals Focus of New IGB Theme

February 9, 2016

Despite dramatic advances in diagnostics and treatment, cancer still accounts for nearly 1 in 4 U.S. deaths, as well as over half of disease-related pet mortality. Using translational approaches to discover new and effective treatments for both is the goal of new research theme Anticancer Discovery from Pets to People (ACPP) at the Carl R. Woese Institute for Genomic Biology. Led by Professor of Chemistry Paul Hergenrother, ACPP will leverage discoveries proved in companion animals such as cats and dogs with cancer to pioneer new drugs and novel targets to treat human cancers.


February 9, 2016


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Cancer drug first tested in pet dogs begins human trials

February 26, 2015

Cancer drug first tested in pet dogs begins human trials

A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma.


February 26, 2015


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