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Research Areas

Mining Microbioal Genomes: Publications

Hellinger, R., Sigurdsson, A., Wu, W., Romanova, E. V., Li, L., Sweedler, J. V., Süssmuth, R. D., & Gruber, C. W. (2023). Peptidomics. Nature Reviews Methods Primers, 3(1), [25].

Choe, K., Jindra, M. A., Hubbard, S. C., Pfleger, B. F., & Sweedler, J. V. (2023). MALDI-MS screening of microbial colonies with isomer resolution to select fatty acid desaturase variants. Analytical Biochemistry, 672, [115169].

Lee, H., Wang, W., Chauhan, N., Xiong, Y., Magazine, N., Valdescruz, O., Kim, D. Y., Qiu, T., Huang, W., Wang, X., & Cunningham, B. T. (2023). Rapid detection of intact SARS-CoV-2 using designer DNA Nets and a pocket-size smartphone-linked fluorimeter. Biosensors and Bioelectronics, 229, [115228].

Cronan, J. E. (2023). How an overlooked gene in coenzyme a synthesis solved an enzyme mechanism predicament. Molecular Microbiology, 119(6), 687-694.

Bown, L., Hirota, R., Goettge, M. N., Cui, J., Krist, D. T., Zhu, L., Giurgiu, C., van der Donk, W. A., Ju, K. S., & Metcalf, W. W. (2023). A Novel Pathway for Biosynthesis of the Herbicidal Phosphonate Natural Product Phosphonothrixin Is Widespread in Actinobacteria. Journal of bacteriology, 205(5), e0048522.

Cunningham, B. T., Bashir, R., Ganguli, A., Damhorst, G. L., Brooks, I., Yu, H., Chen, W., Sun, F., Ornob, A., Nash, D., & Hirschberg, D. L. (2023). System For Rapid, Portable, And Multiplexed Detection And Identification Of Pathogen Specific Nucleic Acid Sequences. (U.S. Patent No. 11654429).

Liu, L., Tibbs, J., Li, N., Bacon, A., Shepherd, S., Lee, H., Chauhan, N., Demirci, U., Wang, X., & Cunningham, B. T. (2023). A photonic resonator interferometric scattering microscope for label-free detection of nanometer-scale objects with digital precision in point-of-use environments. Biosensors and Bioelectronics, 228, [115197].

Volk, M. J., Tran, V. G., Tan, S. I., Mishra, S., Fatma, Z., Boob, A., Li, H., Xue, P., Martin, T. A., & Zhao, H. (2023). Metabolic Engineering: Methodologies and Applications. Chemical reviews, 123(9), 5521-5570.

Mi, X., Desormeaux, E. K., Le, T. T., van der Donk, W. A., & Shukla, D. (2023). Sequence controlled secondary structure is important for the site-selectivity of lanthipeptide cyclization. Chemical Science.

Blin, K., Shaw, S., Augustijn, H. E., Reitz, Z. L., Biermann, F., Alanjary, M., Fetter, A., Terlouw, B. R., Metcalf, W. W., Helfrich, E. J. N., van Wezel, G. P., Medema, M. H., & Weber, T. (2023). antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation. Nucleic acids research, [gkad344].

Castro, D. C., Smith, K. W., Norsworthy, M. D., Rubakhin, S. S., Weisbrod, C. R., Hendrickson, C. L., & Sweedler, J. V. (2023). Single-Cell and Subcellular Analysis Using Ultrahigh Resolution 21 T MALDI FTICR Mass Spectrometry. Analytical Chemistry, 95(17), 6980-6988.

Ranoa, D. R. E., Sharma, P., Schane, C. P., Lewis, A. N., Valdez, E., Marada, V. V. V. R., Hager, M. V., Montgomery, W., Wolf, S. P., Schreiber, K., Schreiber, H., Bailey, K., Fan, T. M., Hergenrother, P. J., Roy, E. J., & Kranz, D. M. (2023). Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. Journal for ImmunoTherapy of Cancer, 11(5).

Sendra, K. M., Barwinska-Sendra, A., Mackenzie, E. S., Baslé, A., Kehl-Fie, T. E., & Waldron, K. J. (2023). An ancient metalloenzyme evolves through metal preference modulation. Nature Ecology and Evolution, 7(5), 732-744.

Serrano, R., Boyko, Y. D., Hernandez, L. W., Lotuzas, A., & Sarlah, D. (2023). Total Syntheses of Scabrolide A and Yonarolide. Journal of the American Chemical Society, 145(16), 8805-8809.

Lee, D. K., Rubakhin, S. S., & Sweedler, J. V. (2023). Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry. Analytical Chemistry, 95(16), 6732-6739.

Wang, X., Shepherd, S., Li, N., Che, C., Song, T., Xiong, Y., Palm, I. R., Zhao, B., Kohli, M., Demirci, U., Lu, Y., & Cunningham, B. T. (2023). A Target Recycling Amplification Process for the Digital Detection of Exosomal MicroRNAs through Photonic Resonator Absorption Microscopy. Angewandte Chemie - International Edition, 62(16), [e202217932].

Park, R., Ongpipattanakul, C., Nair, S. K., Bowers, A. A., & Kuhlman, B. (2023). Designer installation of a substrate recruitment domain to tailor enzyme specificity. Nature chemical biology, 19(4), 460-467.

Yu, T., Cui, H., Li, J. C., Luo, Y., Jiang, G., & Zhao, H. (2023). Enzyme function prediction using contrastive learning. Science, 379(6639), 1358-1363.

Putt, K. S., Tarasow, T., Sandhorst, J. S., Hergenrother, P. J., Fako, V. E., & Peterson, Q. P. (2023). Compounds And Methods For The Treatment Of Cancer. (U.S. Patent No. 11612598).

Danciu, O. C., Holdhoff, M., Peterson, R. A., Fischer, J. H., Liu, L. C., Wang, H., Venepalli, N. K., Chowdhery, R., Nicholas, M. K., Russell, M. J., Fan, T. M., Hergenrother, P. J., Tarasow, T. M., & Dudek, A. Z. (2023). Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies. British Journal of Cancer, 128(5), 783-792.

Xiong, Y., Shepherd, S., Tibbs, J., Bacon, A., Liu, W., Akin, L. D., Ayupova, T., Bhaskar, S., & Cunningham, B. T. (2023). Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications. Micromachines, 14(3), [668].

Padron, G. C., Shuppara, A. M., Sharma, A., Koch, M. D., Palalay, J. J. S., Radin, J. N., Kehl-Fie, T., Imlay, J. A., & Sanfilippo, J. E. (2023). Shear rate sensitizes bacterial pathogens to H2O2 stress. Proceedings of the National Academy of Sciences of the United States of America, 120(11), [e2216774120].

Hu, M., Dinh, H. V., Shen, Y., Suthers, P. F., Foster, C. J., Call, C. M., Ye, X., Pratas, J., Fatma, Z., Zhao, H., Rabinowitz, J. D., & Maranas, C. D. (2023). Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale. Metabolic Engineering, 76, 1-17.

Zhou, S., Fatma, Z., Xue, P., Mishra, S., Cao, M., Zhao, H., & Sweedler, J. V. (2023). Mass Spectrometry-Based High-Throughput Quantification of Bioproducts in Liquid Culture. Analytical Chemistry, 95(8), 4067-4076.

Harley, B. A. C., Lu, Y., Cunningham, B. T., Zhuo, Y., Choi, J. S., Marin, T., & Singamaneni, S. (2023). Photonic Resonator Absorption Microscopy (pram) For Digital Resolution Biomolecular Diagnostics. (U.S. Patent No. 11591640).

Hergenrother, P. J., Shapiro, D. J., & Boudreau, M. W. (2023). Activators Of The Unfolded Protein Response. (U.S. Patent No. 11584718).

Bacon, A., Wang, W., Lee, H., Umrao, S., Sinawang, P. D., Akin, D., Khemtonglang, K., Tan, A., Hirshfield, S., Demirci, U., Wang, X., & Cunningham, B. T. (2023). Review of HIV Self Testing Technologies and Promising Approaches for the Next Generation. Biosensors, 13(2), [298].

Lee, H., Wu, C., Desormeaux, E. K., Sarksian, R., & van der Donk, W. A. (2023). Improved production of class I lanthipeptides in Escherichia coli. Chemical Science, 14(10), 2537-2546.

Wu, T. C., Aguilar-Granda, A., Hotta, K., Yazdani, S. A., Pollice, R., Vestfrid, J., Hao, H., Lavigne, C., Seifrid, M., Angello, N., Bencheikh, F., Hein, J. E., Burke, M., Adachi, C., & Aspuru-Guzik, A. (2023). A Materials Acceleration Platform for Organic Laser Discovery. Advanced Materials, 35(6), [2207070].

Xie, Y. R., Chari, V. K., Castro, D. C., Grant, R., Rubakhin, S. S., & Sweedler, J. V. (2023). Data-Driven and Machine Learning-Based Framework for Image-Guided Single-Cell Mass Spectrometry. Journal of Proteome Research, 22(2), 491-500.

Dong, H., Wang, H., & Cronan, J. E. (2023). Divergent unsaturated fatty acid synthesis in two highly related model pseudomonads. Molecular Microbiology, 119(2), 252-261.

Lei, R., Hernandez Garcia, A., Tan, T. J. C., Teo, Q. W., Wang, Y., Zhang, X., Luo, S., Nair, S. K., Peng, J., & Wu, N. C. (2023). Mutational fitness landscape of human influenza H3N2 neuraminidase. Cell Reports, 42(1), [111951].

Cheong, C. B., Peh, G. R., Wei, Y., Rehka, T., Ang, E. L., Zhao, H., Zhang, C., & Lim, Y. H. (2023). A Spirobicyclo[3.1.0]Terpene from the Investigation of Sesquiterpene Synthases from Lactarius deliciosus. ACS chemical biology, 18(1), 134-140.

Daniels, P. N., & van der Donk, W. A. (2023). Substrate Specificity of the Flavoenzyme BhaC1 That Converts a C-Terminal Trp to a Hydroxyquinone. Biochemistry, 62(2), 378–387.

Ongpipattanakul, C., Liu, S., Luo, Y., Nair, S. K., & Van der donk, W. A. (2023). The mechanism of thia-Michael addition catalyzed by LanC enzymes. Proceedings of the National Academy of Sciences, 120(3), [e2217523120].

Jia, J., Parmar, D., Ellis, J. F., Cao, T., Cutri, A. R., Shrout, J. D., Sweedler, J. V., & Bohn, P. W. (2023). Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. ACS Infectious Diseases, 9(1), 150-161.

Matsuoka, W., Kawahara, K. P., Ito, H., Sarlah, D., & Itami, K. (2023). π-Extended Rubrenes via Dearomative Annulative π-Extension Reaction. Journal of the American Chemical Society, 145(1), 658-666.

Singh, R., Bhagwat, S. S., Viswanathan, M. B., Cortés‐Peña, Y. R., Eilts, K. K., Mcdonough, G., Cao, M., Guest, J. S., Zhao, H., & Singh, V. (2023). Adsorptive separation and recovery of triacetic acid lactone from fermentation broth. Biofuels, Bioproducts and Biorefining, 17(1), 109-120.

Solórzano, P. K. P., Bastille, T. S., Radin, J. N., & Kehl-Fie, T. E. (2023). A Manganese-independent Aldolase Enables Staphylococcus aureus To Resist Host-imposed Metal Starvation. mBio, 14(1).

Shelton, K. E., & Mitchell, D. A. (2023). Bioinformatic prediction and experimental validation of RiPP recognition elements. In A. K. Shukla (Ed.), Integrated Methods in Protein Biochemistry: Part B (pp. 191-233). (Methods in Enzymology; Vol. 679). Academic Press Inc..

Mishra, S., Wang, Z., Volk, M. J., & Zhao, H. (2023). Design and application of a kinetic model of lipid metabolism in Saccharomyces cerevisiae. Metabolic Engineering, 75, 12-18.

Zheng, Y., & Nair, S. K. (2023). YcaO-mediated ATP-dependent peptidase activity in ribosomal peptide biosynthesis. Nature chemical biology, 19(1), 111-119.

Anmangandla, A., Jana, S., Peng, K., Wallace, S. D., Bagde, S. R., Drown, B. S., Xu, J., Hergenrother, P. J., Fromme, J. C., & Lin, H. (Accepted/In press). A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology.

Ayikpoe, R. S., Zhu, L., Chen, J. Y., Ting, C. P., & van der Donk, W. A. (Accepted/In press). Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692. ACS Central Science.

Long, C. C., Antevska, A., Mast, D. H., Okyem, S., Sweedler, J. V., & Do, T. D. (Accepted/In press). Nonenzymatic Posttranslational Modifications and Peptide Cleavages Observed in Peptide Epimers. Journal of the American Society for Mass Spectrometry.

Castro, D. C., Chan-Andersen, P., Romanova, E. V., & Sweedler, J. V. (Accepted/In press). Probe-based mass spectrometry approaches for single-cell and single-organelle measurements. Mass Spectrometry Reviews.

Lee, H., Wang, W., Chauhan, N., Xiong, Y., Magazine, N., Valdescruz, O., Kim, D. Y., Qiu, T., Huang, W., Wang, X., & Cunningham, B. T. (2023). Rapid, sensitive detection of intact SARS-CoV-2 using DNA nets and a smartphone-linked fluorimeter. In G. L. Cote (Ed.), Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics [123870B] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12387). SPIE.

Li, G., Jeon, C. K., Ma, M., Jia, Y., Zheng, Z., Delafield, D. G., Lu, G., Romanova, E. V., Sweedler, J. V., Ruotolo, B. T., & Li, L. (Accepted/In press). Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42. Chemical Science.

Wang, W., Lee, H., Jankelow, A. M., Hoang, T. H., Bacon, A., Sun, F., Chae, S., Kindratenko, V., Koprowski, K., Stavins, R. A., Ceriani, D., Engelder, Z., King, W. P., Do, M. N., Bashir, R., Valera, E., & Cunningham, B. T. (2023). Smartphone Clip-On Instrument and Microfluidic Processor for Rapid Sample-to-Answer Detection of Zika Virus in Whole Blood Using Spatial RT-LAMP. In G. L. Cote (Ed.), Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics [123870D] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12387). SPIE.

Cunningham, B. T. (2023). Ultrasensitive and ultra selective liquid biopsy: Nanophotonics-driven digital resolution biomolecule sensing combined with target molecule recycling. In R. R. Alfano, & A. B. Seddon (Eds.), Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis [1237304] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12373). SPIE.

Milenkovic, O., Hernandez, A. G., Zhao, H., & Tabatabaei, S. (2022). Nick-based Data Storage In Native Nucleic Acids. (U.S. Patent No. 11538554).

Cabrera, A., Edelstein, H. I., Glykofrydis, F., Love, K. S., Palacios, S., Tycko, J., Zhang, M., Lensch, S., Shields, C. E., Livingston, M., Weiss, R., Zhao, H., Haynes, K. A., Morsut, L., Chen, Y. Y., Khalil, A. S., Wong, W. W., Collins, J. J., Rosser, S. J., ... Deans, T. L. (2022). The sound of silence: Transgene silencing in mammalian cell engineering. Cell Systems, 13(12), 950-973.

Liu, Y., Wei, Y., Teh, T. M., Liu, D., Zhou, Y., Zhao, S., Ang, E. L., Zhao, H., & Zhang, Y. (2022). Identification and Characterization of the Biosynthetic Pathway of the Sulfonolipid Capnine. Biochemistry, 61(24), 2861-2869.

Burke, M. D., Fan, T. M., Hergenrother, P. J., Brooke, C. B., Ranoa, D. R. E., Holland, R. L., Alnaji, F. G., Green, K. J., & Wang, L. (2022). Saliva-based Molecular Testing For SARS-CoV-2. (U.S. Patent No. 11530457).

Huck, C. J., Boyko, Y. D., & Sarlah, D. (2022). Erratum: Correction: Dearomative logic in natural product total synthesis (Natural product reports (2022)). Natural Product Reports, 39(12), 2336-2337.

Sarksian, R., Zhu, L., & Van der donk, W. A. (2022). syn-Elimination of glutamylated threonine in lanthipeptide biosynthesis. Chemical Communications, 59(9), 1165-1168.

Shi, W., Bell, S., Iyer, H., Brenden, C. K., Zhang, Y., Kim, S., Park, I., Bashir, R., Sweedler, J., & Vlasov, Y. (2022). Integrated silicon microfluidic chip for picoliter-scale analyte segmentation and microscale printing for mass spectrometry imaging. Lab on a chip, 23(1), 72-80.

Burke, M. D., & Grillo, A. S. (2022). Restoring Physiology In Iron-deficient Organisms Using Small Molecules. (U.S. Patent No. 11517540).

Ayikpoe, R. S., Shi, C., Battiste, A. J., Eslami, S. M., Ramesh, S., Simon, M. A., Bothwell, I. R., Lee, H., Rice, A. J., Ren, H., Tian, Q., Harris, L. A., Sarksian, R., Zhu, L., Frerk, A. M., Precord, T. W., van der Donk, W. A., Mitchell, D. A., & Zhao, H. (2022). A scalable platform to discover antimicrobials of ribosomal origin. Nature communications, 13(1), [6135].

Ju, K. S., & Nair, S. K. (2022). Convergent and divergent biosynthetic strategies towards phosphonic acid natural products. Current Opinion in Chemical Biology, 71, [102214].

Peng, Q., Huang, Z., Sun, K., Liu, Y., Yoon, C. W., Harrison, R. E. S., Schmitt, D. L., Zhu, L., Wu, Y., Tasan, I., Zhao, H., Zhang, J., Zhong, S., Chien, S., & Wang, Y. (2022). Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells. Nature communications, 13(1), [7933].

Schultz, J. C., Mishra, S., Gaither, E., Mejia, A., Dinh, H., Maranas, C., & Zhao, H. (2022). Metabolic engineering of Rhodotorula toruloides IFO0880 improves C16 and C18 fatty alcohol production from synthetic media. Microbial cell factories, 21(1), [26].

Ranoa, D. R. E., Holland, R. L., Alnaji, F. G., Green, K. J., Wang, L., Fredrickson, R. L., Wang, T., Wong, G. N., Uelmen, J., Maslov, S., Weiner, Z. J., Tkachenko, A. V., Zhang, H., Liu, Z., Ibrahim, A., Patel, S. J., Paul, J. M., Vance, N. P., Gulick, J. G., ... Burke, M. D. (2022). Mitigation of SARS-CoV-2 transmission at a large public university. Nature communications, 13(1), [3207].

Enghiad, B., Xue, P., Singh, N., Boob, A. G., Shi, C., Petrov, V. A., Liu, R., Peri, S. S., Lane, S. T., Gaither, E. D., & Zhao, H. (2022). PlasmidMaker is a versatile, automated, and high throughput end-to-end platform for plasmid construction. Nature communications, 13(1), [2697].

Lei, R., Tan, T. J. C., Hernandez Garcia, A., Wang, Y., Diefenbacher, M., Teo, C., Gopan, G., Tavakoli Dargani, Z., Teo, Q. W., Graham, C. S., Brooke, C. B., Nair, S. K., & Wu, N. C. (2022). Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase. Nature communications, 13(1), [6443].

Revie, N. M., Iyer, K. R., Maxson, M. E., Zhang, J., Yan, S., Fernandes, C. M., Meyer, K. J., Chen, X., Skulska, I., Fogal, M., Sanchez, H., Hossain, S., Li, S., Yashiroda, Y., Hirano, H., Yoshida, M., Osada, H., Boone, C., Shapiro, R. S., ... Cowen, L. E. (2022). Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation. Nature communications, 13(1), [3634].

Li, S., Jira, E. R., Angello, N. H., Li, J., Yu, H., Moore, J. S., Diao, Y., Burke, M. D., & Schroeder, C. M. (2022). Using automated synthesis to understand the role of side chains on molecular charge transport. Nature communications, 13(1), [2102].

Tarasow, T., Peh, J., Hergenrother, P. J., & Boudreau, M. W. (2022). Cancer Therapy By Degrading Dual Mek Signaling. (U.S. Patent No. 11510919).

Rice, A. J., Pelton, J. M., Kramer, N. J., Catlin, D. S., Nair, S. K., Pogorelov, T. V., Mitchell, D. A., & Bowers, A. A. (2022). Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis. Journal of the American Chemical Society, 144(46), 21116-21124.

Zheng, Y., Ongpipattanakul, C., & Nair, S. K. (2022). Bioconjugate Platform for Iterative Backbone N-Methylation of Peptides. ACS Catalysis, 12(22), 14006-14014.

Ornelas, M. Y., Thomas, A. Y., Johnson Rosas, L. I., Scoville, R. O., & Mehta, A. P. (2022). Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes. ACS synthetic biology, 11(11), 3759-3771.

Zhao, H. (2022). The Ever-Expanding Boundaries of Synthetic Biology. ACS synthetic biology, 11(11), 3550.

Hooper, A. R., Oštrek, A., Milian-Lopez, A., & Sarlah, D. (2022). Bioinspired Total Synthesis of Pyritide A2 through Pyridine Ring Synthesis. Angewandte Chemie - International Edition, 61(46), [e202212299].

Zhao, F., Wei, Y., Wang, X., Zhou, Y., Tong, Y., Ang, E. L., Liu, S., Zhao, H., & Zhang, Y. (2022). Enzymatic Synthesis of the Unnatural Nucleotide 2’-Deoxyisoguanosine 5’-Monophosphate. ChemBioChem, 23(21), [e202200295].

Roy, P., Dennis, D. G., Eschbach, M. D., Anand, S. D., Xu, F., Maturano, J., Hellman, J., Sarlah, D., & Das, A. (2022). Metabolites of Cannabigerol Generated by Human Cytochrome P450s Are Bioactive. Biochemistry, 61(21), 2398-2408.

Qiao, W., Xu, S., Liu, Z., Fu, X., Zhao, H., & Shi, S. (2022). Challenges and opportunities in C1-based biomanufacturing. Bioresource Technology, 364, [128095].

Dong, H., & Cronan, J. E. (2022). Unsaturated fatty acid synthesis in Enterococcus faecalis requires a specific enoyl-ACP reductase. Molecular Microbiology, 118(5), 541-551.

Angello, N. H., Rathore, V., Beker, W., Wołos, A., Jira, E. R., Roszak, R., Wu, T. C., Schroeder, C. M., Aspuru-Guzik, A., Grzybowski, B. A., & Burke, M. D. (2022). Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling. Science, 378(6618), 399-405.

Zhang, Z., & Zhao, H. (2022). Tunnel engineering enables multifaceted improvements in halogenase. Chem Catalysis, 2(10), 2432-2434.

Zhang, Y., Li, K., Zhao, Y., Shi, W., Iyer, H., Kim, S., Brenden, C., Sweedler, J. V., & Vlasov, Y. (2022). Attomole-Level Multiplexed Detection of Neurochemicals in Picoliter Droplets by On-Chip Nanoelectrospray Ionization Coupled to Mass Spectrometry. Analytical Chemistry, 94(40), 13804-13809.

Muñoz, K. A., & Hergenrother, P. J. (2022). Computational discovery of dynobactin antibiotics. Nature Microbiology, 7(10), 1512-1513.

Ali, A., Davidson, S., Fraenkel, E., Gilmore, I., Hankemeier, T., Kirwan, J. A., Lane, A. N., Lanekoff, I., Larion, M., McCall, L. I., Murphy, M., Sweedler, J. V., & Zhu, C. (2022). Single cell metabolism: current and future trends. Metabolomics, 18(10), [77].

Huck, C. J., Boyko, Y. D., & Sarlah, D. (2022). Dearomative logic in natural product total synthesis. Natural Product Reports, 39(12), 2231-2291.

Lee, Y. G., Kim, C., Kuanyshev, N., Kang, N. K., Fatma, Z., Wu, Z. Y., Cheng, M. H., Singh, V., Yoshikuni, Y., Zhao, H., & Jin, Y. S. (2022). Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates. Journal of Agricultural and Food Chemistry, 70(38), 12085-12094.

Pei, Z. F., Zhu, L., Sarksian, R., Van Der Donk, W. A., & Nair, S. K. (2022). Class v Lanthipeptide Cyclase Directs the Biosynthesis of a Stapled Peptide Natural Product. Journal of the American Chemical Society, 144(38), 17549-17557.

Parker, E. N., Cain, B. N., Hajian, B., Ulrich, R. J., Geddes, E. J., Barkho, S., Lee, H. Y., Williams, J. D., Raynor, M., Caridha, D., Zaino, A., Rohde, J. M., Zak, M., Shekhar, M., Muñoz, K. A., Rzasa, K. M., Temple, E. R., Hunt, D., Jin, X., ... Hergenrother, P. J. (2022). Erratum: An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections (ACS Central Science (2022) 8:8 (1145-1158) DOI: 10.1021/acscentsci.2c00598). ACS Central Science, 8(9), 1362.

Ongpipattanakul, C., Desormeaux, E. K., Dicaprio, A., Van Der Donk, W. A., Mitchell, D. A., & Nair, S. K. (2022). Mechanism of Action of Ribosomally Synthesized and Post-Translationally Modified Peptides. Chemical reviews, 122(18), 14722-14814.

Sarksian, R., & Van Der Donk, W. A. (2022). Divergent Evolution of Lanthipeptide Stereochemistry. ACS chemical biology, 17(9), 2551-2558.

Liang, H., Lopez, I. J., Sánchez-Hidalgo, M., Genilloud, O., & Van Der Donk, W. A. (2022). Mechanistic Studies on Dehydration in Class v Lanthipeptides. ACS chemical biology, 17(9), 2519-2527.

Piacentini, P., Bingham, T. W., & Sarlah, D. (2022). Dearomative Ring Expansion of Polycyclic Arenes. Angewandte Chemie - International Edition, 61(36), [e202208014].

Laporte, A. J., Shi, Y., Hein, J. E., & Burke, M. D. (2022). Stereospecific Csp3Suzuki-Miyaura Cross-Coupling That Evades β-Oxygen Elimination. ACS Catalysis, 12(17), 10905-10912.

Lloyd, C. T., Iwig, D. F., Wang, B., Cossu, M., Metcalf, W. W., Boal, A. K., & Booker, S. J. (2022). Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609(7925), 197-203.

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