Hellinger, R., Sigurdsson, A., Wu, W., Romanova, E. V., Li, L., Sweedler, J. V., Süssmuth, R. D., & Gruber, C. W. (2023). Peptidomics. Nature Reviews Methods Primers, 3(1), [25]. https://doi.org/10.1038/s43586-023-00205-2
Choe, K., Jindra, M. A., Hubbard, S. C., Pfleger, B. F., & Sweedler, J. V. (2023). MALDI-MS screening of microbial colonies with isomer resolution to select fatty acid desaturase variants. Analytical Biochemistry, 672, [115169]. https://doi.org/10.1016/j.ab.2023.115169
Lee, H., Wang, W., Chauhan, N., Xiong, Y., Magazine, N., Valdescruz, O., Kim, D. Y., Qiu, T., Huang, W., Wang, X., & Cunningham, B. T. (2023). Rapid detection of intact SARS-CoV-2 using designer DNA Nets and a pocket-size smartphone-linked fluorimeter. Biosensors and Bioelectronics, 229, [115228]. https://doi.org/10.1016/j.bios.2023.115228
Cronan, J. E. (2023). How an overlooked gene in coenzyme a synthesis solved an enzyme mechanism predicament. Molecular Microbiology, 119(6), 687-694. https://doi.org/10.1111/mmi.15070
Bown, L., Hirota, R., Goettge, M. N., Cui, J., Krist, D. T., Zhu, L., Giurgiu, C., van der Donk, W. A., Ju, K. S., & Metcalf, W. W. (2023). A Novel Pathway for Biosynthesis of the Herbicidal Phosphonate Natural Product Phosphonothrixin Is Widespread in Actinobacteria. Journal of bacteriology, 205(5), e0048522. https://doi.org/10.1128/jb.00485-22
Cunningham, B. T., Bashir, R., Ganguli, A., Damhorst, G. L., Brooks, I., Yu, H., Chen, W., Sun, F., Ornob, A., Nash, D., & Hirschberg, D. L. (2023). System For Rapid, Portable, And Multiplexed Detection And Identification Of Pathogen Specific Nucleic Acid Sequences. (U.S. Patent No. 11654429).
Liu, L., Tibbs, J., Li, N., Bacon, A., Shepherd, S., Lee, H., Chauhan, N., Demirci, U., Wang, X., & Cunningham, B. T. (2023). A photonic resonator interferometric scattering microscope for label-free detection of nanometer-scale objects with digital precision in point-of-use environments. Biosensors and Bioelectronics, 228, [115197]. https://doi.org/10.1016/j.bios.2023.115197
Volk, M. J., Tran, V. G., Tan, S. I., Mishra, S., Fatma, Z., Boob, A., Li, H., Xue, P., Martin, T. A., & Zhao, H. (2023). Metabolic Engineering: Methodologies and Applications. Chemical reviews, 123(9), 5521-5570. https://doi.org/10.1021/acs.chemrev.2c00403
Mi, X., Desormeaux, E. K., Le, T. T., van der Donk, W. A., & Shukla, D. (2023). Sequence controlled secondary structure is important for the site-selectivity of lanthipeptide cyclization. Chemical Science. https://doi.org/10.1039/D2SC06546K
Blin, K., Shaw, S., Augustijn, H. E., Reitz, Z. L., Biermann, F., Alanjary, M., Fetter, A., Terlouw, B. R., Metcalf, W. W., Helfrich, E. J. N., van Wezel, G. P., Medema, M. H., & Weber, T. (2023). antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation. Nucleic acids research, [gkad344]. https://doi.org/10.1093/nar/gkad344
Castro, D. C., Smith, K. W., Norsworthy, M. D., Rubakhin, S. S., Weisbrod, C. R., Hendrickson, C. L., & Sweedler, J. V. (2023). Single-Cell and Subcellular Analysis Using Ultrahigh Resolution 21 T MALDI FTICR Mass Spectrometry. Analytical Chemistry, 95(17), 6980-6988. https://doi.org/10.1021/acs.analchem.3c00393
Ranoa, D. R. E., Sharma, P., Schane, C. P., Lewis, A. N., Valdez, E., Marada, V. V. V. R., Hager, M. V., Montgomery, W., Wolf, S. P., Schreiber, K., Schreiber, H., Bailey, K., Fan, T. M., Hergenrother, P. J., Roy, E. J., & Kranz, D. M. (2023). Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. Journal for ImmunoTherapy of Cancer, 11(5). https://doi.org/10.1136/jitc-2022-006509
Sendra, K. M., Barwinska-Sendra, A., Mackenzie, E. S., Baslé, A., Kehl-Fie, T. E., & Waldron, K. J. (2023). An ancient metalloenzyme evolves through metal preference modulation. Nature Ecology and Evolution, 7(5), 732-744. https://doi.org/10.1038/s41559-023-02012-0
Serrano, R., Boyko, Y. D., Hernandez, L. W., Lotuzas, A., & Sarlah, D. (2023). Total Syntheses of Scabrolide A and Yonarolide. Journal of the American Chemical Society, 145(16), 8805-8809. https://doi.org/10.1021/jacs.3c02317
Lee, D. K., Rubakhin, S. S., & Sweedler, J. V. (2023). Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry. Analytical Chemistry, 95(16), 6732-6739. https://doi.org/10.1021/acs.analchem.3c00612
Wang, X., Shepherd, S., Li, N., Che, C., Song, T., Xiong, Y., Palm, I. R., Zhao, B., Kohli, M., Demirci, U., Lu, Y., & Cunningham, B. T. (2023). A Target Recycling Amplification Process for the Digital Detection of Exosomal MicroRNAs through Photonic Resonator Absorption Microscopy. Angewandte Chemie - International Edition, 62(16), [e202217932]. https://doi.org/10.1002/anie.202217932
Park, R., Ongpipattanakul, C., Nair, S. K., Bowers, A. A., & Kuhlman, B. (2023). Designer installation of a substrate recruitment domain to tailor enzyme specificity. Nature chemical biology, 19(4), 460-467. https://doi.org/10.1038/s41589-022-01206-0
Yu, T., Cui, H., Li, J. C., Luo, Y., Jiang, G., & Zhao, H. (2023). Enzyme function prediction using contrastive learning. Science, 379(6639), 1358-1363. https://doi.org/10.1126/science.adf2465
Putt, K. S., Tarasow, T., Sandhorst, J. S., Hergenrother, P. J., Fako, V. E., & Peterson, Q. P. (2023). Compounds And Methods For The Treatment Of Cancer. (U.S. Patent No. 11612598).
Danciu, O. C., Holdhoff, M., Peterson, R. A., Fischer, J. H., Liu, L. C., Wang, H., Venepalli, N. K., Chowdhery, R., Nicholas, M. K., Russell, M. J., Fan, T. M., Hergenrother, P. J., Tarasow, T. M., & Dudek, A. Z. (2023). Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies. British Journal of Cancer, 128(5), 783-792. https://doi.org/10.1038/s41416-022-02089-7
Xiong, Y., Shepherd, S., Tibbs, J., Bacon, A., Liu, W., Akin, L. D., Ayupova, T., Bhaskar, S., & Cunningham, B. T. (2023). Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications. Micromachines, 14(3), [668]. https://doi.org/10.3390/mi14030668
Padron, G. C., Shuppara, A. M., Sharma, A., Koch, M. D., Palalay, J. J. S., Radin, J. N., Kehl-Fie, T., Imlay, J. A., & Sanfilippo, J. E. (2023). Shear rate sensitizes bacterial pathogens to H2O2 stress. Proceedings of the National Academy of Sciences of the United States of America, 120(11), [e2216774120]. https://doi.org/10.1073/pnas.2216774120
Hu, M., Dinh, H. V., Shen, Y., Suthers, P. F., Foster, C. J., Call, C. M., Ye, X., Pratas, J., Fatma, Z., Zhao, H., Rabinowitz, J. D., & Maranas, C. D. (2023). Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale. Metabolic Engineering, 76, 1-17. https://doi.org/10.1016/j.ymben.2023.01.001
Zhou, S., Fatma, Z., Xue, P., Mishra, S., Cao, M., Zhao, H., & Sweedler, J. V. (2023). Mass Spectrometry-Based High-Throughput Quantification of Bioproducts in Liquid Culture. Analytical Chemistry, 95(8), 4067-4076. https://doi.org/10.1021/acs.analchem.2c04845
Harley, B. A. C., Lu, Y., Cunningham, B. T., Zhuo, Y., Choi, J. S., Marin, T., & Singamaneni, S. (2023). Photonic Resonator Absorption Microscopy (pram) For Digital Resolution Biomolecular Diagnostics. (U.S. Patent No. 11591640).
Hergenrother, P. J., Shapiro, D. J., & Boudreau, M. W. (2023). Activators Of The Unfolded Protein Response. (U.S. Patent No. 11584718).
Bacon, A., Wang, W., Lee, H., Umrao, S., Sinawang, P. D., Akin, D., Khemtonglang, K., Tan, A., Hirshfield, S., Demirci, U., Wang, X., & Cunningham, B. T. (2023). Review of HIV Self Testing Technologies and Promising Approaches for the Next Generation. Biosensors, 13(2), [298]. https://doi.org/10.3390/bios13020298
Lee, H., Wu, C., Desormeaux, E. K., Sarksian, R., & van der Donk, W. A. (2023). Improved production of class I lanthipeptides in Escherichia coli. Chemical Science, 14(10), 2537-2546. https://doi.org/10.1039/d2sc06597e
Wu, T. C., Aguilar-Granda, A., Hotta, K., Yazdani, S. A., Pollice, R., Vestfrid, J., Hao, H., Lavigne, C., Seifrid, M., Angello, N., Bencheikh, F., Hein, J. E., Burke, M., Adachi, C., & Aspuru-Guzik, A. (2023). A Materials Acceleration Platform for Organic Laser Discovery. Advanced Materials, 35(6), [2207070]. https://doi.org/10.1002/adma.202207070
Xie, Y. R., Chari, V. K., Castro, D. C., Grant, R., Rubakhin, S. S., & Sweedler, J. V. (2023). Data-Driven and Machine Learning-Based Framework for Image-Guided Single-Cell Mass Spectrometry. Journal of Proteome Research, 22(2), 491-500. https://doi.org/10.1021/acs.jproteome.2c00714
Dong, H., Wang, H., & Cronan, J. E. (2023). Divergent unsaturated fatty acid synthesis in two highly related model pseudomonads. Molecular Microbiology, 119(2), 252-261. https://doi.org/10.1111/mmi.15018
Lei, R., Hernandez Garcia, A., Tan, T. J. C., Teo, Q. W., Wang, Y., Zhang, X., Luo, S., Nair, S. K., Peng, J., & Wu, N. C. (2023). Mutational fitness landscape of human influenza H3N2 neuraminidase. Cell Reports, 42(1), [111951]. https://doi.org/10.1016/j.celrep.2022.111951
Cheong, C. B., Peh, G. R., Wei, Y., Rehka, T., Ang, E. L., Zhao, H., Zhang, C., & Lim, Y. H. (2023). A Spirobicyclo[3.1.0]Terpene from the Investigation of Sesquiterpene Synthases from Lactarius deliciosus. ACS chemical biology, 18(1), 134-140. https://doi.org/10.1021/acschembio.2c00760
Daniels, P. N., & van der Donk, W. A. (2023). Substrate Specificity of the Flavoenzyme BhaC1 That Converts a C-Terminal Trp to a Hydroxyquinone. Biochemistry, 62(2), 378–387. https://doi.org/10.1021/acs.biochem.2c00206
Ongpipattanakul, C., Liu, S., Luo, Y., Nair, S. K., & Van der donk, W. A. (2023). The mechanism of thia-Michael addition catalyzed by LanC enzymes. Proceedings of the National Academy of Sciences, 120(3), [e2217523120]. https://doi.org/10.1073/pnas.2217523120
Jia, J., Parmar, D., Ellis, J. F., Cao, T., Cutri, A. R., Shrout, J. D., Sweedler, J. V., & Bohn, P. W. (2023). Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. ACS Infectious Diseases, 9(1), 150-161. https://doi.org/10.1021/acsinfecdis.2c00519
Matsuoka, W., Kawahara, K. P., Ito, H., Sarlah, D., & Itami, K. (2023). π-Extended Rubrenes via Dearomative Annulative π-Extension Reaction. Journal of the American Chemical Society, 145(1), 658-666. https://doi.org/10.1021/jacs.2c11338
Singh, R., Bhagwat, S. S., Viswanathan, M. B., Cortés‐Peña, Y. R., Eilts, K. K., Mcdonough, G., Cao, M., Guest, J. S., Zhao, H., & Singh, V. (2023). Adsorptive separation and recovery of triacetic acid lactone from fermentation broth. Biofuels, Bioproducts and Biorefining, 17(1), 109-120. https://doi.org/10.1002/bbb.2427
Solórzano, P. K. P., Bastille, T. S., Radin, J. N., & Kehl-Fie, T. E. (2023). A Manganese-independent Aldolase Enables Staphylococcus aureus To Resist Host-imposed Metal Starvation. mBio, 14(1). https://doi.org/10.1128/mbio.03223-22
Shelton, K. E., & Mitchell, D. A. (2023). Bioinformatic prediction and experimental validation of RiPP recognition elements. In A. K. Shukla (Ed.), Integrated Methods in Protein Biochemistry: Part B (pp. 191-233). (Methods in Enzymology; Vol. 679). Academic Press Inc.. https://doi.org/10.1016/bs.mie.2022.08.050
Mishra, S., Wang, Z., Volk, M. J., & Zhao, H. (2023). Design and application of a kinetic model of lipid metabolism in Saccharomyces cerevisiae. Metabolic Engineering, 75, 12-18. https://doi.org/10.1016/j.ymben.2022.11.003
Zheng, Y., & Nair, S. K. (2023). YcaO-mediated ATP-dependent peptidase activity in ribosomal peptide biosynthesis. Nature chemical biology, 19(1), 111-119. https://doi.org/10.1038/s41589-022-01141-0
Anmangandla, A., Jana, S., Peng, K., Wallace, S. D., Bagde, S. R., Drown, B. S., Xu, J., Hergenrother, P. J., Fromme, J. C., & Lin, H. (Accepted/In press). A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology. https://doi.org/10.1021/acschembio.3c00092
Ayikpoe, R. S., Zhu, L., Chen, J. Y., Ting, C. P., & van der Donk, W. A. (Accepted/In press). Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692. ACS Central Science. https://doi.org/10.1021/acscentsci.3c00160
Long, C. C., Antevska, A., Mast, D. H., Okyem, S., Sweedler, J. V., & Do, T. D. (Accepted/In press). Nonenzymatic Posttranslational Modifications and Peptide Cleavages Observed in Peptide Epimers. Journal of the American Society for Mass Spectrometry. https://doi.org/10.1021/jasms.3c00092
Castro, D. C., Chan-Andersen, P., Romanova, E. V., & Sweedler, J. V. (Accepted/In press). Probe-based mass spectrometry approaches for single-cell and single-organelle measurements. Mass Spectrometry Reviews. https://doi.org/10.1002/mas.21841
Lee, H., Wang, W., Chauhan, N., Xiong, Y., Magazine, N., Valdescruz, O., Kim, D. Y., Qiu, T., Huang, W., Wang, X., & Cunningham, B. T. (2023). Rapid, sensitive detection of intact SARS-CoV-2 using DNA nets and a smartphone-linked fluorimeter. In G. L. Cote (Ed.), Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics [123870B] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12387). SPIE. https://doi.org/10.1117/12.2650836
Li, G., Jeon, C. K., Ma, M., Jia, Y., Zheng, Z., Delafield, D. G., Lu, G., Romanova, E. V., Sweedler, J. V., Ruotolo, B. T., & Li, L. (Accepted/In press). Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42. Chemical Science. https://doi.org/10.1039/d3sc00678f
Wang, W., Lee, H., Jankelow, A. M., Hoang, T. H., Bacon, A., Sun, F., Chae, S., Kindratenko, V., Koprowski, K., Stavins, R. A., Ceriani, D., Engelder, Z., King, W. P., Do, M. N., Bashir, R., Valera, E., & Cunningham, B. T. (2023). Smartphone Clip-On Instrument and Microfluidic Processor for Rapid Sample-to-Answer Detection of Zika Virus in Whole Blood Using Spatial RT-LAMP. In G. L. Cote (Ed.), Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics [123870D] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12387). SPIE. https://doi.org/10.1117/12.2649267
Cunningham, B. T. (2023). Ultrasensitive and ultra selective liquid biopsy: Nanophotonics-driven digital resolution biomolecule sensing combined with target molecule recycling. In R. R. Alfano, & A. B. Seddon (Eds.), Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis [1237304] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12373). SPIE. https://doi.org/10.1117/12.2659440
Milenkovic, O., Hernandez, A. G., Zhao, H., & Tabatabaei, S. (2022). Nick-based Data Storage In Native Nucleic Acids. (U.S. Patent No. 11538554).
Cabrera, A., Edelstein, H. I., Glykofrydis, F., Love, K. S., Palacios, S., Tycko, J., Zhang, M., Lensch, S., Shields, C. E., Livingston, M., Weiss, R., Zhao, H., Haynes, K. A., Morsut, L., Chen, Y. Y., Khalil, A. S., Wong, W. W., Collins, J. J., Rosser, S. J., ... Deans, T. L. (2022). The sound of silence: Transgene silencing in mammalian cell engineering. Cell Systems, 13(12), 950-973. https://doi.org/10.1016/j.cels.2022.11.005
Liu, Y., Wei, Y., Teh, T. M., Liu, D., Zhou, Y., Zhao, S., Ang, E. L., Zhao, H., & Zhang, Y. (2022). Identification and Characterization of the Biosynthetic Pathway of the Sulfonolipid Capnine. Biochemistry, 61(24), 2861-2869. https://doi.org/10.1021/acs.biochem.2c00102
Burke, M. D., Fan, T. M., Hergenrother, P. J., Brooke, C. B., Ranoa, D. R. E., Holland, R. L., Alnaji, F. G., Green, K. J., & Wang, L. (2022). Saliva-based Molecular Testing For SARS-CoV-2. (U.S. Patent No. 11530457).
Huck, C. J., Boyko, Y. D., & Sarlah, D. (2022). Erratum: Correction: Dearomative logic in natural product total synthesis (Natural product reports (2022)). Natural Product Reports, 39(12), 2336-2337. https://doi.org/10.1039/d2np90039d
Sarksian, R., Zhu, L., & Van der donk, W. A. (2022). syn-Elimination of glutamylated threonine in lanthipeptide biosynthesis. Chemical Communications, 59(9), 1165-1168. https://doi.org/10.1039/D2CC06345J
Shi, W., Bell, S., Iyer, H., Brenden, C. K., Zhang, Y., Kim, S., Park, I., Bashir, R., Sweedler, J., & Vlasov, Y. (2022). Integrated silicon microfluidic chip for picoliter-scale analyte segmentation and microscale printing for mass spectrometry imaging. Lab on a chip, 23(1), 72-80. https://doi.org/10.1039/d2lc00688j
Burke, M. D., & Grillo, A. S. (2022). Restoring Physiology In Iron-deficient Organisms Using Small Molecules. (U.S. Patent No. 11517540).
Ayikpoe, R. S., Shi, C., Battiste, A. J., Eslami, S. M., Ramesh, S., Simon, M. A., Bothwell, I. R., Lee, H., Rice, A. J., Ren, H., Tian, Q., Harris, L. A., Sarksian, R., Zhu, L., Frerk, A. M., Precord, T. W., van der Donk, W. A., Mitchell, D. A., & Zhao, H. (2022). A scalable platform to discover antimicrobials of ribosomal origin. Nature communications, 13(1), [6135]. https://doi.org/10.1038/s41467-022-33890-w
Ju, K. S., & Nair, S. K. (2022). Convergent and divergent biosynthetic strategies towards phosphonic acid natural products. Current Opinion in Chemical Biology, 71, [102214]. https://doi.org/10.1016/j.cbpa.2022.102214
Peng, Q., Huang, Z., Sun, K., Liu, Y., Yoon, C. W., Harrison, R. E. S., Schmitt, D. L., Zhu, L., Wu, Y., Tasan, I., Zhao, H., Zhang, J., Zhong, S., Chien, S., & Wang, Y. (2022). Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells. Nature communications, 13(1), [7933]. https://doi.org/10.1038/s41467-022-35504-x
Schultz, J. C., Mishra, S., Gaither, E., Mejia, A., Dinh, H., Maranas, C., & Zhao, H. (2022). Metabolic engineering of Rhodotorula toruloides IFO0880 improves C16 and C18 fatty alcohol production from synthetic media. Microbial cell factories, 21(1), [26]. https://doi.org/10.1186/s12934-022-01750-3
Ranoa, D. R. E., Holland, R. L., Alnaji, F. G., Green, K. J., Wang, L., Fredrickson, R. L., Wang, T., Wong, G. N., Uelmen, J., Maslov, S., Weiner, Z. J., Tkachenko, A. V., Zhang, H., Liu, Z., Ibrahim, A., Patel, S. J., Paul, J. M., Vance, N. P., Gulick, J. G., ... Burke, M. D. (2022). Mitigation of SARS-CoV-2 transmission at a large public university. Nature communications, 13(1), [3207]. https://doi.org/10.1038/s41467-022-30833-3
Enghiad, B., Xue, P., Singh, N., Boob, A. G., Shi, C., Petrov, V. A., Liu, R., Peri, S. S., Lane, S. T., Gaither, E. D., & Zhao, H. (2022). PlasmidMaker is a versatile, automated, and high throughput end-to-end platform for plasmid construction. Nature communications, 13(1), [2697]. https://doi.org/10.1038/s41467-022-30355-y
Lei, R., Tan, T. J. C., Hernandez Garcia, A., Wang, Y., Diefenbacher, M., Teo, C., Gopan, G., Tavakoli Dargani, Z., Teo, Q. W., Graham, C. S., Brooke, C. B., Nair, S. K., & Wu, N. C. (2022). Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase. Nature communications, 13(1), [6443]. https://doi.org/10.1038/s41467-022-34060-8
Revie, N. M., Iyer, K. R., Maxson, M. E., Zhang, J., Yan, S., Fernandes, C. M., Meyer, K. J., Chen, X., Skulska, I., Fogal, M., Sanchez, H., Hossain, S., Li, S., Yashiroda, Y., Hirano, H., Yoshida, M., Osada, H., Boone, C., Shapiro, R. S., ... Cowen, L. E. (2022). Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation. Nature communications, 13(1), [3634]. https://doi.org/10.1038/s41467-022-31308-1
Li, S., Jira, E. R., Angello, N. H., Li, J., Yu, H., Moore, J. S., Diao, Y., Burke, M. D., & Schroeder, C. M. (2022). Using automated synthesis to understand the role of side chains on molecular charge transport. Nature communications, 13(1), [2102]. https://doi.org/10.1038/s41467-022-29796-2
Tarasow, T., Peh, J., Hergenrother, P. J., & Boudreau, M. W. (2022). Cancer Therapy By Degrading Dual Mek Signaling. (U.S. Patent No. 11510919).
Rice, A. J., Pelton, J. M., Kramer, N. J., Catlin, D. S., Nair, S. K., Pogorelov, T. V., Mitchell, D. A., & Bowers, A. A. (2022). Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis. Journal of the American Chemical Society, 144(46), 21116-21124. https://doi.org/10.1021/jacs.2c07377
Zheng, Y., Ongpipattanakul, C., & Nair, S. K. (2022). Bioconjugate Platform for Iterative Backbone N-Methylation of Peptides. ACS Catalysis, 12(22), 14006-14014. https://doi.org/10.1021/acscatal.2c04681
Ornelas, M. Y., Thomas, A. Y., Johnson Rosas, L. I., Scoville, R. O., & Mehta, A. P. (2022). Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes. ACS synthetic biology, 11(11), 3759-3771. https://doi.org/10.1021/acssynbio.2c00359
Zhao, H. (2022). The Ever-Expanding Boundaries of Synthetic Biology. ACS synthetic biology, 11(11), 3550. https://doi.org/10.1021/acssynbio.2c00582
Hooper, A. R., Oštrek, A., Milian-Lopez, A., & Sarlah, D. (2022). Bioinspired Total Synthesis of Pyritide A2 through Pyridine Ring Synthesis. Angewandte Chemie - International Edition, 61(46), [e202212299]. https://doi.org/10.1002/anie.202212299
Zhao, F., Wei, Y., Wang, X., Zhou, Y., Tong, Y., Ang, E. L., Liu, S., Zhao, H., & Zhang, Y. (2022). Enzymatic Synthesis of the Unnatural Nucleotide 2’-Deoxyisoguanosine 5’-Monophosphate. ChemBioChem, 23(21), [e202200295]. https://doi.org/10.1002/cbic.202200295
Roy, P., Dennis, D. G., Eschbach, M. D., Anand, S. D., Xu, F., Maturano, J., Hellman, J., Sarlah, D., & Das, A. (2022). Metabolites of Cannabigerol Generated by Human Cytochrome P450s Are Bioactive. Biochemistry, 61(21), 2398-2408. https://doi.org/10.1021/acs.biochem.2c00383
Qiao, W., Xu, S., Liu, Z., Fu, X., Zhao, H., & Shi, S. (2022). Challenges and opportunities in C1-based biomanufacturing. Bioresource Technology, 364, [128095]. https://doi.org/10.1016/j.biortech.2022.128095
Dong, H., & Cronan, J. E. (2022). Unsaturated fatty acid synthesis in Enterococcus faecalis requires a specific enoyl-ACP reductase. Molecular Microbiology, 118(5), 541-551. https://doi.org/10.1111/mmi.14981
Angello, N. H., Rathore, V., Beker, W., Wołos, A., Jira, E. R., Roszak, R., Wu, T. C., Schroeder, C. M., Aspuru-Guzik, A., Grzybowski, B. A., & Burke, M. D. (2022). Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling. Science, 378(6618), 399-405. https://doi.org/10.1126/science.adc8743
Zhang, Z., & Zhao, H. (2022). Tunnel engineering enables multifaceted improvements in halogenase. Chem Catalysis, 2(10), 2432-2434. https://doi.org/10.1016/j.checat.2022.09.010
Zhang, Y., Li, K., Zhao, Y., Shi, W., Iyer, H., Kim, S., Brenden, C., Sweedler, J. V., & Vlasov, Y. (2022). Attomole-Level Multiplexed Detection of Neurochemicals in Picoliter Droplets by On-Chip Nanoelectrospray Ionization Coupled to Mass Spectrometry. Analytical Chemistry, 94(40), 13804-13809. https://doi.org/10.1021/acs.analchem.2c02323
Muñoz, K. A., & Hergenrother, P. J. (2022). Computational discovery of dynobactin antibiotics. Nature Microbiology, 7(10), 1512-1513. https://doi.org/10.1038/s41564-022-01234-5
Ali, A., Davidson, S., Fraenkel, E., Gilmore, I., Hankemeier, T., Kirwan, J. A., Lane, A. N., Lanekoff, I., Larion, M., McCall, L. I., Murphy, M., Sweedler, J. V., & Zhu, C. (2022). Single cell metabolism: current and future trends. Metabolomics, 18(10), [77]. https://doi.org/10.1007/s11306-022-01934-3
Huck, C. J., Boyko, Y. D., & Sarlah, D. (2022). Dearomative logic in natural product total synthesis. Natural Product Reports, 39(12), 2231-2291. https://doi.org/10.1039/d2np00042c
Lee, Y. G., Kim, C., Kuanyshev, N., Kang, N. K., Fatma, Z., Wu, Z. Y., Cheng, M. H., Singh, V., Yoshikuni, Y., Zhao, H., & Jin, Y. S. (2022). Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates. Journal of Agricultural and Food Chemistry, 70(38), 12085-12094. https://doi.org/10.1021/acs.jafc.2c04251
Pei, Z. F., Zhu, L., Sarksian, R., Van Der Donk, W. A., & Nair, S. K. (2022). Class v Lanthipeptide Cyclase Directs the Biosynthesis of a Stapled Peptide Natural Product. Journal of the American Chemical Society, 144(38), 17549-17557. https://doi.org/10.1021/jacs.2c06808
Parker, E. N., Cain, B. N., Hajian, B., Ulrich, R. J., Geddes, E. J., Barkho, S., Lee, H. Y., Williams, J. D., Raynor, M., Caridha, D., Zaino, A., Rohde, J. M., Zak, M., Shekhar, M., Muñoz, K. A., Rzasa, K. M., Temple, E. R., Hunt, D., Jin, X., ... Hergenrother, P. J. (2022). Erratum: An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections (ACS Central Science (2022) 8:8 (1145-1158) DOI: 10.1021/acscentsci.2c00598). ACS Central Science, 8(9), 1362. https://doi.org/10.1021/acscentsci.2c00969
Ongpipattanakul, C., Desormeaux, E. K., Dicaprio, A., Van Der Donk, W. A., Mitchell, D. A., & Nair, S. K. (2022). Mechanism of Action of Ribosomally Synthesized and Post-Translationally Modified Peptides. Chemical reviews, 122(18), 14722-14814. https://doi.org/10.1021/acs.chemrev.2c00210
Sarksian, R., & Van Der Donk, W. A. (2022). Divergent Evolution of Lanthipeptide Stereochemistry. ACS chemical biology, 17(9), 2551-2558. https://doi.org/10.1021/acschembio.2c00492
Liang, H., Lopez, I. J., Sánchez-Hidalgo, M., Genilloud, O., & Van Der Donk, W. A. (2022). Mechanistic Studies on Dehydration in Class v Lanthipeptides. ACS chemical biology, 17(9), 2519-2527. https://doi.org/10.1021/acschembio.2c00458
Piacentini, P., Bingham, T. W., & Sarlah, D. (2022). Dearomative Ring Expansion of Polycyclic Arenes. Angewandte Chemie - International Edition, 61(36), [e202208014]. https://doi.org/10.1002/anie.202208014
Laporte, A. J., Shi, Y., Hein, J. E., & Burke, M. D. (2022). Stereospecific Csp3Suzuki-Miyaura Cross-Coupling That Evades β-Oxygen Elimination. ACS Catalysis, 12(17), 10905-10912. https://doi.org/10.1021/acscatal.2c03245
Lloyd, C. T., Iwig, D. F., Wang, B., Cossu, M., Metcalf, W. W., Boal, A. K., & Booker, S. J. (2022). Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609(7925), 197-203. https://doi.org/10.1038/s41586-022-05120-2
Lee, C. J., Schnieders, J. H., Rubakhin, S. S., Patel, A. V., Liu, C., Naji, A., & Sweedler, J. V. (2022). d-Amino Acids and Classical Neurotransmitters in Healthy and Type 2 Diabetes-Affected Human Pancreatic Islets of Langerhans. Metabolites, 12(9), [799]. https://doi.org/10.3390/metabo12090799
Cao, M., Tran, V. G., Qin, J., Olson, A., Mishra, S., Schultz, JC., Huang, C., Xie, D., & Zhao, H. (2022). Metabolic engineering of oleaginous yeast Rhodotorula toruloides for overproduction of triacetic acid lactone. Biotechnology and bioengineering, 119(9), 2529-2540. https://doi.org/10.1002/bit.28159
Dong, H., & Cronan, J. E. (2022). The Two Acyl Carrier Proteins of Enterococcus faecalis Have Nonredundant Functions. Journal of bacteriology, 204(9). https://doi.org/10.1128/jb.00202-22
Parker, E. N., Cain, B. N., Hajian, B., Ulrich, R. J., Geddes, E. J., Barkho, S., Lee, H. Y., Williams, J. D., Raynor, M., Caridha, D., Zaino, A., Shekhar, M., Muñoz, K. A., Rzasa, K. M., Temple, E. R., Hunt, D., Jin, X., Vuong, C., Pannone, K., ... Hergenrother, P. J. (2022). An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections. ACS Central Science, 8(8), 1145-1158. https://doi.org/10.1021/acscentsci.2c00598
Nesic, M., Ryffel, D. B., Maturano, J., Shevlin, M., Pollack, S. R., Gauthier, D. R., Trigo-Mouriño, P., Zhang, L. K., Schultz, D. M., McCabe Dunn, J. M., Campeau, L. C., Patel, N. R., Petrone, D. A., & Sarlah, D. (2022). Total Synthesis of Darobactin A. Journal of the American Chemical Society, 144(31), 14026-14030. https://doi.org/10.1021/jacs.2c05891
Rymut, H. E., Rund, L. A., Southey, B. R., Johnson, R. W., Sweedler, J. V., & Rodriguez-Zas, S. L. (2022). Prefrontal Cortex Response to Prenatal Insult and Postnatal Opioid Exposure. Genes, 13(8), [1371]. https://doi.org/10.3390/genes13081371
Chan-Andersen, P. C., Romanova, E. V., Rubakhin, S. S., & Sweedler, J. V. (2022). Profiling 26,000 Aplysia californica neurons by single cell mass spectrometry reveals neuronal populations with distinct neuropeptide profiles. Journal of Biological Chemistry, 298(8), [102254]. https://doi.org/10.1016/j.jbc.2022.102254
Lee, C. J., Qiu, T. A., Hong, Z., Zhang, Z., Min, Y., Zhang, L., Dai, L., Zhao, H., Si, T., & Sweedler, J. V. (2022). Profiling of d-alanine production by the microbial isolates of rat gut microbiota. FASEB Journal, 36(8), [e22446]. https://doi.org/10.1096/fj.202101595R
Chauhan, N., Xiong, Y., Ren, S., Dwivedy, A., Magazine, N., Zhou, L., Jin, X., Zhang, T., Cunningham, B. T., Yao, S., Huang, W., & Wang, X. (2022). Net-Shaped DNA Nanostructures Designed for Rapid/Sensitive Detection and Potential Inhibition of the SARS-CoV-2 Virus. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.2c04835
Parkinson, E. I., Lakkis, H. G., Alwali, A. A., Metcalf, M. E. M., Modi, R., & Metcalf, W. W. (2022). An Unusual Oxidative Rearrangement Catalyzed by a Divergent Member of the 2-Oxoglutarate-Dependent Dioxygenase Superfamily during Biosynthesis of Dehydrofosmidomycin. Angewandte Chemie - International Edition, 61(30), [e202206173]. https://doi.org/10.1002/anie.202206173
Yu, Y., & van der Donk, W. A. (2022). Biosynthesis of 3-thia-α-amino acids on a carrier peptide. Proceedings of the National Academy of Sciences of the United States of America, 119(29), [e2205285119]. https://doi.org/10.1073/pnas.2205285119
Zhao, H. (2022). Synthetic Biology 2.0: The Dawn of a New Era. ACS synthetic biology, 11(7), 2221. https://doi.org/10.1021/acssynbio.2c00332
Kelly, A. M., Berry, M. R., Tasker, S. Z., McKee, S. A., Fan, T. M., & Hergenrother, P. J. (2022). Target-Agnostic P-Glycoprotein Assessment Yields Strategies to Evade Efflux, Leading to a BRAF Inhibitor with Intracranial Efficacy. Journal of the American Chemical Society, 144(27), 12367-12380. https://doi.org/10.1021/jacs.2c03944
Charbonnier, M., González-Espinoza, G., Kehl-Fie, T. E., & Lalaouna, D. (2022). Battle for Metals: Regulatory RNAs at the Front Line. Frontiers in Cellular and Infection Microbiology, 12, [952948]. https://doi.org/10.3389/fcimb.2022.952948
Huang, X., Feng, J., Cui, J., Jiang, G., Harrison, W., Zang, X., Zhou, J., Wang, B., & Zhao, H. (2022). Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition. Nature Catalysis, 5(7), 586-593. https://doi.org/10.1038/s41929-022-00777-4
Nguyen, D. T., Le, T. T., Rice, A. J., Hudson, G. A., Van Der Donk, W. A., & Mitchell, D. A. (2022). Accessing Diverse Pyridine-Based Macrocyclic Peptides by a Two-Site Recognition Pathway. Journal of the American Chemical Society, 144(25), 11263-11269. https://doi.org/10.1021/jacs.2c02824
Ekaputri, S., Choi, E. K., Sabelli, M., Aring, L., Green, K. J., Chang, J. O., Bao, K., Choi, H. S., Iwase, S., Kim, J., Corradini, E., Pietrangelo, A., Burke, M. D., & Seo, Y. A. (2022). A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages. Proceedings of the National Academy of Sciences, 119(26), [e2121400119]. https://doi.org/10.1073/pnas.2121400119
Jankelow, A. M., Lee, H., Wang, W., Hoang, T. H., Bacon, A., Sun, F., Chae, S., Kindratenko, V., Koprowski, K., Stavins, R. A., Ceriani, D. D., Engelder, Z. W., King, W. P., Do, M. N., Bashir, R., Valera, E., & Cunningham, B. T. (2022). Smartphone clip-on instrument and microfluidic processor for rapid sample-to-answer detection of Zika virus in whole blood using spatial RT-LAMP. Analyst, 147(17), 3838-3853. https://doi.org/10.1039/d2an00438k
Bubliauskas, A., Blair, D. J., Powell-Davies, H., Kitson, P. J., Burke, M. D., & Cronin, L. (2022). Digitizing Chemical Synthesis in 3D Printed Reactionware. Angewandte Chemie - International Edition, 61(24), [e202116108]. https://doi.org/10.1002/anie.202116108
Duan, Y., Wei, Y., Xing, M., Liu, J., Jiang, L., Lu, Q., Liu, X., Liu, Y., Ang, E. L., Liao, R. Z., Yuchi, Z., Zhao, H., & Zhang, Y. (2022). Anaerobic Hydroxyproline Degradation Involving C-N Cleavage by a Glycyl Radical Enzyme. Journal of the American Chemical Society, 144(22), 9715-9722. https://doi.org/10.1021/jacs.2c01673
Cronan, J. E., & Luk, T. (2022). Advances in the Structural Biology, Mechanism, and Physiology of Cyclopropane Fatty Acid Modifications of Bacterial Membranes. Microbiology and Molecular Biology Reviews, 86(2). https://doi.org/10.1128/mmbr.00013-22
Burcham, L. R., Akbari, M. S., Alhajjar, N., Keogh, R. A., Radin, J. N., Kehl-Fie, T. E., Belew, A. T., El-Sayed, N. M., McIver, K. S., & Doran, K. S. (2022). Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization. mBio, 13(3). https://doi.org/10.1128/mbio.00985-22
Hong, Y., Qin, J., Verderosa, A. D., Hawas, S., Zhang, B., Blaskovich, M. A. T., Cronan, J. E., & Totsika, M. (2022). Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics. mSphere, 7(3). https://doi.org/10.1128/msphere.00117-22
Melzer, M. E., Sweedler, J. V., & Clark, K. D. (2022). Rapid Determination of RNA Modifications in Consensus Motifs by Nuclease Protection with Ion-Tagged Oligonucleotide Probes and Matrix-Assisted Laser Desorption Ionization Mass Spectrometry. Genes, 13(6), [1008]. https://doi.org/10.3390/genes13061008
Murphy, S. E., & Sweedler, J. V. (2022). Metabolomics-based mass spectrometry methods to analyze the chemical content of 3D organoid models. Analyst, 147(13), 2918-2929. https://doi.org/10.1039/d2an00599a
Gu, W., Zheng, Y., Pogorelov, T., Nair, S. K., & Schmidt, E. W. (2022). Control of Nucleophile Chemoselectivity in Cyanobactin YcaO Heterocyclases PatD and TruD. ACS chemical biology, 17(5), 1215–1225. https://doi.org/10.1021/acschembio.2c00147
Boudreau, M. W., & Hergenrother, P. J. (2022). Evolution of 3-(4-hydroxyphenyl)indoline-2-one as a scaffold for potent and selective anticancer activity. RSC Medicinal Chemistry, 13(6), 711-725. https://doi.org/10.1039/d2md00110a
Spietz, R. L., Payne, D., Kulkarni, G., Metcalf, W. W., Roden, E. E., & Boyd, E. S. (2022). Investigating Abiotic and Biotic Mechanisms of Pyrite Reduction. Frontiers in Microbiology, 13, [878387]. https://doi.org/10.3389/fmicb.2022.878387
Dennis, D. G., Anand, S. D., Lopez, A. J., Petrovčič, J., Das, A., & Sarlah, D. (2022). Synthesis of the Cannabimovone and Cannabifuran Class of Minor Phytocannabinoids and Their Anti-inflammatory Activity. Journal of Organic Chemistry, 87(9), 6075-6086. https://doi.org/10.1021/acs.joc.2c00336
Zheng, Y., Cong, Y., Schmidt, E. W., & Nair, S. K. (2022). Catalysts for the Enzymatic Lipidation of Peptides. Accounts of chemical research, 55(9), 1313-1323. https://doi.org/10.1021/acs.accounts.2c00108
Zhao, B., Wang, W., Li, N., Garcia-Lezana, T., Che, C., Wang, X., Losic, B., Villanueva, A., & Cunningham, B. T. (2022). Digital-resolution and highly sensitive detection of multiple exosomal small RNAs by DNA toehold probe-based photonic resonator absorption microscopy. Talanta, 241, [123256]. https://doi.org/10.1016/j.talanta.2022.123256
Diefenbacher, M., Tan, T. J. C., Bauer, D. L. V., Stadtmueller, B. M., Wu, N. C., & Brooke, C. B. (2022). Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression. Journal of virology, 96(10). https://doi.org/10.1128/jvi.00205-22
Frye, K. A., Sendra, K. M., Waldron, K. J., & Kehl-Fie, T. E. (2022). Old dogs, new tricks: New insights into the iron/manganese superoxide dismutase family. Journal of Inorganic Biochemistry, 230, [111748]. https://doi.org/10.1016/j.jinorgbio.2022.111748
Zou, Q., Dong, H., Zhu, L., & Cronan, J. E. (2022). The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids. Frontiers in Microbiology, 13, [877582]. https://doi.org/10.3389/fmicb.2022.877582
Harrison, W., Huang, X., & Zhao, H. (2022). Photobiocatalysis for Abiological Transformations. Accounts of chemical research, 55(8), 1087-1096. https://doi.org/10.1021/acs.accounts.1c00719
David, B. M., Wyllie, R. M., Harouaka, R., & Jensen, P. A. (2022). A reinforcement learning framework for pooled oligonucleotide design. Bioinformatics, 38(8), 2219-2225. https://doi.org/10.1093/bioinformatics/btac073
McLaughlin, M. I., Yu, Y., & Van Der Donk, W. A. (2022). Substrate Recognition by the Peptidyl-(S)-2-mercaptoglycine Synthase TglHI during 3-Thiaglutamate Biosynthesis. ACS chemical biology, 17(4), 930-940. https://doi.org/10.1021/acschembio.2c00087
Sarksian, R., Hegemann, J. D., Simon, M. A., Acedo, J. Z., & Van Der Donk, W. A. (2022). Unexpected Methyllanthionine Stereochemistry in the Morphogenetic Lanthipeptide SapT. Journal of the American Chemical Society, 144(14), 6373-6382. https://doi.org/10.1021/jacs.2c00517
Blair, D. J., Chitti, S., Trobe, M., Kostyra, D. M., Haley, H. M. S., Hansen, R. L., Ballmer, S. G., Woods, T. J., Wang, W., Mubayi, V., Schmidt, M. J., Pipal, R. W., Morehouse, G. F., Palazzolo Ray, A. M. E., Gray, D. L., Gill, A. L., & Burke, M. D. (2022). Automated iterative Csp3-C bond formation. Nature, 604(7904), 92-97. https://doi.org/10.1038/s41586-022-04491-w
Xie, Y. R., Castro, D. C., Rubakhin, S. S., Sweedler, J. V., & Lam, F. (2022). Enhancing the Throughput of FT Mass Spectrometry Imaging Using Joint Compressed Sensing and Subspace Modeling. Analytical Chemistry, 94(13), 5335-5343. https://doi.org/10.1021/acs.analchem.1c05279
Song, K., Minami, J. K., Huang, A., Dehkordi, S. R., Lomeli, S. H., Luebeck, J., Goodman, M. H., Moriceau, G., Krijgsman, O., Dharanipragada, P., Ridgley, T., Crosson, W. P., Salazar, J., Pazol, E., Karin, G., Jayaraman, R., Balanis, N. G., Alhani, S., Sheu, K., ... Graeber, T. G. (2022). Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges. Cancer Discovery, 12(4), 1046-1069. https://doi.org/10.1158/2159-8290.CD-20-0936
Clark, K. D., Rubakhin, S. S., & Sweedler, J. V. (2022). Characterizing RNA Modifications in Single Neurons using Mass Spectrometry. Journal of Visualized Experiments, 2022(182), [e63940]. https://doi.org/10.3791/63940
Cogan, D. P., Bhushan, A., Reyes, R., Zhu, L., Piel, J., & Nair, S. K. (2022). Structure and mechanism for iterative amide N-methylation in the biosynthesis of channel-forming peptide cytotoxins. Proceedings of the National Academy of Sciences of the United States of America, 119(13), [e2116578119]. https://doi.org/10.1073/pnas.2116578119
Beker, W., Roszak, R., Wolos, A., Angello, N. H., Rathore, V., Burke, M. D., & Grzybowski, B. A. (2022). Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki-Miyaura Coupling. Journal of the American Chemical Society, 144(11), 4819-4827. https://doi.org/10.1021/jacs.1c12005
Lundahl, M. N., Sarksian, R., Yang, H., Jodts, R. J., Pagnier, A., Smith, D. F., Mosquera, M. A., Van Der Donk, W. A., Hoffman, B. M., Broderick, W. E., & Broderick, J. B. (2022). Mechanism of Radical S-Adenosyl- l -methionine Adenosylation: Radical Intermediates and the Catalytic Competence of the 5′-Deoxyadenosyl Radical. Journal of the American Chemical Society, 144(11), 5087-5098. https://doi.org/10.1021/jacs.1c13706
Wu, YF., Toba, E. A. D. L., Dvoretskiy, S., Jung, R., Kim, N., Daniels, L., Romanova, E. V., Drnevich, J., Sweedler, J. V., & Boppart, M. D. (Accepted/In press). Development of a cell‐free strategy to recover aged skeletal muscle after disuse. The Journal of Physiology. https://doi.org/10.1113/JP282867
Hergenrother, P. J., & Riley, A. (2022). Topoisomerase inhibitors with antibacterial and anticancer activity. (U.S. Patent No. 11274106).
Boudreau, M. W., Mulligan, M. P., Shapiro, D. J., Fan, T. M., & Hergenrother, P. J. (2022). Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer. Journal of Medicinal Chemistry, 65(5), 3894-3912. https://doi.org/10.1021/acs.jmedchem.1c01730
Tran, V. G., & Zhao, H. (2022). Engineering robust microorganisms for organic acid production. Journal of Industrial Microbiology and Biotechnology, 49(2), [kuab067]. https://doi.org/10.1093/jimb/kuab067
Zhao, H., & Enghiad, B. (2022). Programmable DNA-guided artificial restriction enzymes. (U.S. Patent No. 11261483).
Ding, W., Meng, Q., Dong, G., Qi, N., Zhao, H., & Shi, S. (2022). Metabolic engineering of threonine catabolism enables Saccharomyces cerevisiae to produce propionate under aerobic conditions. Biotechnology Journal, 17(3), [2100579]. https://doi.org/10.1002/biot.202100579
Che, C., Xue, R., Li, N., Gupta, P., Wang, X., Zhao, B., Singamaneni, S., Nie, S., & Cunningham, B. T. (2022). Accelerated Digital Biodetection Using Magneto-plasmonic Nanoparticle-Coupled Photonic Resonator Absorption Microscopy. ACS Nano, 16(2), 2345–2354. https://doi.org/10.1021/acsnano.1c08569
Vasan, A. K., Haloi, N., Ulrich, R. J., Metcalf, M. E., Wen, P. C., Metcalf, W. W., Hergenrother, P. J., Shukla, D., & Tajkhorshid, E. (2022). Role of internal loop dynamics in antibiotic permeability of outer membrane porins. Proceedings of the National Academy of Sciences of the United States of America, 119(8), [e2117009119]. https://doi.org/10.1073/pnas.2117009119
Liang, J., Zhang, H., Tan, Y. L., Zhao, H., & Ang, E. L. (2022). Directed Evolution of Replication-Competent Double-Stranded DNA Bacteriophage toward New Host Specificity. ACS synthetic biology, 11(2), 634-643. https://doi.org/10.1021/acssynbio.1c00319
Svec, R. L., Mckee, S. A., Berry, M. R., Kelly, A. M., Fan, T. M., & Hergenrother, P. J. (2022). Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture. ACS chemical biology, 17(2), 299–313. https://doi.org/10.1021/acschembio.2c00022
Oberg, N., Precord, T. W., Mitchell, D. A., & Gerlt, J. A. (2022). RadicalSAM.org: A Resource to Interpret Sequence-Function Space and Discover New Radical SAM Enzyme Chemistry. ACS Bio and Med Chem Au, 2(1), 22-35. https://doi.org/10.1021/acsbiomedchemau.1c00048
Li, N., Wang, X., Tibbs, J., Che, C., Peinetti, A. S., Zhao, B., Liu, L., Barya, P., Cooper, L., Rong, L., Wang, X., Lu, Y., & Cunningham, B. T. (2022). Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy. Journal of the American Chemical Society, 144(4), 1498-1502. https://doi.org/10.1021/jacs.1c09579
Xiong, Y., Li, N., Che, C., Wang, W., Barya, P., Liu, W., Liu, L., Wang, X., Wu, S., Hu, H., & Cunningham, B. T. (2022). Microscopies Enabled by Photonic Metamaterials. Sensors, 22(3), [1086]. https://doi.org/10.3390/s22031086
Dainton, A. N., He, F., Bingham, T. W., Sarlah, D., Detweiler, K. B., Mangian, H. J., & De Godoy, M. R. C. (2022). Nutritional and physico-chemical implications of avocado meal as a novel dietary fiber source in an extruded canine diet. Journal of animal science, 100(2), [skac026]. https://doi.org/10.1093/jas/skac026
Li, N., Zhao, B., Stavins, R., Peinetti, A. S., Chauhan, N., Bashir, R., Cunningham, B. T., King, W. P., Lu, Y., Wang, X., & Valera, E. (2022). Overcoming the limitations of COVID-19 diagnostics with nanostructures, nucleic acid engineering, and additive manufacturing. Current Opinion in Solid State and Materials Science, 26(1), [100966]. https://doi.org/10.1016/j.cossms.2021.100966
Zhang, Y., Kim, S., Shi, W., Zhao, Y., Park, I., Brenden, C., Iyer, H., Jha, P., Bashir, R., Sweedler, J. V., & Vlasov, Y. (2022). Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform. Lab on a chip, 22(1), 40-46. https://doi.org/10.1039/d1lc00758k
Daniels, P. N., Lee, H., Splain, R. A., Ting, C. P., Zhu, L., Zhao, X., Moore, B. S., & van der Donk, W. A. (2022). A biosynthetic pathway to aromatic amines that uses glycyl-tRNA as nitrogen donor. Nature Chemistry, 14(1), 71-77. https://doi.org/10.1038/s41557-021-00802-2
Bingham, T. W., Hernandez, L. W., & Sarlah, D. (2022). Amaryllidaceae isocarbostyril alkaloids. In M. Harmata (Ed.), Strategies and Tactics in Organic Synthesis (Vol. 15, pp. 1-52). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-822212-6.00004-7
Harris, L. A., & Mitchell, D. A. (2022). Reactivity-based screening for natural product discovery. In E. E. Carlson (Ed.), Chemical Microbiology Part B (pp. 177-208). (Methods in Enzymology; Vol. 665). Academic Press Inc.. https://doi.org/10.1016/bs.mie.2021.11.018
Mathieu, V., Laguera, B., Masi, M., Dulanto, S. A., Bingham, T. W., Hernandez, L. W., Sarlah, D., Evidente, A., Lafontaine, D. L. J., Kornienko, A., & Lane, M. A. (2022). Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells. Biomolecules, 12(9). https://doi.org/10.3390/biom12091267
De Crécy-Lagard, V., Amorin De Hegedus, R., Arighi, C., Babor, J., Bateman, A., Blaby, I., Blaby-Haas, C., Bridge, A. J., Burley, S. K., Cleveland, S., Colwell, L. J., Conesa, A., Dallago, C., Danchin, A., De Waard, A., Deutschbauer, A., Dias, R., Ding, Y., Fang, G., ... Xu, J. (2022). A roadmap for the functional annotation of protein families: A community perspective. Database, 2022, [baac062]. https://doi.org/10.1093/database/baac062
De La Toba, E. A., Anapindi, K. D. B., & Sweedler, J. V. (Accepted/In press). Assessment and Comparison of Database Search Engines for Peptidomic Applications. Journal of Proteome Research. https://doi.org/10.1021/acs.jproteome.2c00307
Lu, T., Qi, F., Ner, J., Feng, T., Cunningham, B., & Peng, L. (2022). GeauxTrace: A Scalable Privacy-Protecting Contact Tracing App Design Using Blockchain. In Proceedings - 2022 IEEE/ACM 9th International Conference on Big Data Computing, Applications and Technologies, BDCAT 2022 (pp. 100-109). (Proceedings - 2022 IEEE/ACM 9th International Conference on Big Data Computing, Applications and Technologies, BDCAT 2022). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BDCAT56447.2022.00020
Thomsen, J., Weidenbach, K., Metcalf, W. W., & Schmitz, R. A. (2022). Genetic Methods and Construction of Chromosomal Mutations in Methanogenic Archaea. In Methods in Molecular Biology (pp. 105-117). (Methods in Molecular Biology; Vol. 2522). Humana Press Inc.. https://doi.org/10.1007/978-1-0716-2445-6_6
Rubakhin, S. S., Romanova, E. V., & Sweedler, J. V. (2022). High-Throughput Image-Guided Microprobe Mass Spectrometric Analysis of Single Cells. In Neuromethods (pp. 115-163). (Neuromethods; Vol. 184). Humana Press Inc.. https://doi.org/10.1007/978-1-0716-2525-5_6
Xiong, X., Tasan, I., Yang, C., Zhang, M., Hernandez Gonzalez, G. A., Liu, S., Chaturvedi, P., Belmont, A. S., & Zhao, H. (Accepted/In press). Imaging Method Using CRISPR/dCas9 and Engineered gRNA Scaffolds Can Perturb Replication Timing at the HSPA1 Locus. ACS synthetic biology. https://doi.org/10.1021/acssynbio.2c00433
Lee, H., & Van Der Donk, W. A. (2022). Macrocyclization and Backbone Modification in RiPP Biosynthesis. Annual review of biochemistry, 91, 269-294. https://doi.org/10.1146/annurev-biochem-032620-104956
Anapindi, K. D. B., Romanova, E. V., Checco, J. W., & Sweedler, J. V. (2022). Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics. Pharmacological Reviews, 74(3), 662-679. https://doi.org/10.1124/pharmrev.121.000423
De La Toba, E. A., Bell, S. E., Romanova, E. V., & Sweedler, J. V. (2022). Mass Spectrometry Measurements of Neuropeptides: From Identification to Quantitation. Annual Review of Analytical Chemistry, 15, 83-106. https://doi.org/10.1146/annurev-anchem-061020-022048
Xiong, Y., Huang, Q., Canady, T. D., Barya, P., Liu, S., Arogundade, O. H., Race, C. M., Wang, X., Zhou, L., Wang, X., Kohli, M., Smith, A. M., & Cunningham, B. T. (2022). Photonic Crystal Enhanced Emission and Blinking Suppression for Single Quantum Dot Digital Resolution Biosensing of Cancer-associated miRNA Biomarkers. In CLEO: Science and Innovations, S and I 2022 [JTh6A.2] (Optics InfoBase Conference Papers). Optica Publishing Group (formerly OSA).
Xiong, Y., Huang, Q., Canady, T. D., Barya, P., Liu, S., Arogundade, O. H., Race, C. M., Wang, X., Zhou, L., Wang, X., Kohli, M., Smith, A. M., & Cunningham, B. T. (2022). Photonic Crystal Enhanced Emission and Blinking Suppression for Single Quantum Dot Digital Resolution Biosensing of Cancer-associated miRNA Biomarkers. In 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings [JTh6A.2] (2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings). Institute of Electrical and Electronics Engineers Inc..
Xiong, Y., Huang, Q., Canady, T. D., Barya, P., Liu, S., Arogundade, O. H., Race, C. M., Che, C., Wang, X., Zhou, L., Igarashi, A., Wang, X., Kohli, M., Smith, A. M., & Cunningham, B. T. (2022). Photonic Crystal Enhanced Quantum Dot Biosensor for Cancer-associated miRNA Detection. In 2022 IEEE Sensors, SENSORS 2022 - Conference Proceedings (Proceedings of IEEE Sensors; Vol. 2022-October). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SENSORS52175.2022.9967032
Li, N., Wang, X., Tibbs, J., Canady, T. D., Huang, Q., Fried, G. A., Wang, X., Cooper, L., Rong, L., Lu, Y., & Cunningham, B. T. (2022). Photonic resonator interferometric scattering microscopy. In S. M. Garcia-Blanco, & P. Cheben (Eds.), Integrated Optics: Devices, Materials, and Technologies XXVI [120040K] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12004). SPIE. https://doi.org/10.1117/12.2606436
Sweedler, J. V., Eberwine, J., & Fraser, S. E. (2022). Preface. Neuromethods, 184, vii-ix.
Chen, P. J., Kelly, A. M., Blair, D. J., & Burke, M. D. (2022). Preparation of MIDA Anhydride and Reaction with Boronic Acids. Organic Syntheses, 99, 92-112. https://doi.org/10.15227/orgsyn.099.0092
Chauhan, N., Wang, W., Lee, H. K., Xiong, Y., Zhang, T., Magazine, N., Peng, L., Zhou, L., Huang, W., Wang, X., & Cunningham, B. T. (2022). V-Pods: Rapid, Sensitive Detection of Intact SARS-CoV-2 using DNA Nets and a Smartphone-Linked Fluorimeter. In B. M. Cullum, D. Kiehl, & E. S. McLamore (Eds.), Smart Biomedical and Physiological Sensor Technology XIX [1212306] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12123). SPIE. https://doi.org/10.1117/12.2617550
