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David Kranz

CAR-T immune therapy attacks ovarian cancer in mice with a single dose

August 1, 2023

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor cancer that has eluded such therapies until now. 


August 1, 2023


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Engineered immune cells recognize, attack solid-tumor cancer cells

July 1, 2020

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia. It modifies a patient’s own T-cells by adding a piece of an antibody that recognizes unique features on the surface of cancer cells. In a new study, researchers report that they have dramatically broadened the potential targets of this approach – their engineered T-cells attack a variety of solid-tumor cancer cells from humans and mice.


July 1, 2020


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