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Carl R. Woese Institute for Genomic Biology

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Research Areas

Lehmann, J. W., Crouch, I. T., Blair, D. J., Trobe, M., Wang, P., Li, J., & Burke, M. (2019). Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp 3 boronic acids Nature communications, 10(1), [1263]. https://doi.org/10.1038/s41467-019-09249-z

Hillson, N., Caddick, M., Cai, Y., Carrasco, J. A., Chang, M. W., Curach, N. C., ... Freemont, P. S. (2019). Building a global alliance of biofoundries. Nature communications, 10(1), [2040]. https://doi.org/10.1038/s41467-019-10079-2

Xing, M., Wei, Y., Zhou, Y., Zhang, J., Lin, L., Hu, Y., ... Zhang, Y. (2019). Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nature communications, 10(1), [1609]. https://doi.org/10.1038/s41467-019-09618-8

Thirawatananond, P., McPherson, R. L., Malhi, J., Nathan, S., Lambrecht, M. J., Brichacek, M., ... Gabelli, S. B. (2019). Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Scientific Reports, 9(1), [5940]. https://doi.org/10.1038/s41598-019-39491-w

Kondakova, T., Kumar, S., & Cronan, J. E. (2019). A novel synthesis of trans-unsaturated fatty acids by the Gram-positive commensal bacterium Enterococcus faecalis FA2-2. Chemistry and Physics of Lipids, 222, 23-35. https://doi.org/10.1016/j.chemphyslip.2019.04.010

Srinivas, S., & Cronan, J. E. (2019). Coping with inadvertent lysis of Escherichia coli cultures: Strains resistant to lysogeny and infection by the stealthy lysogenic phage Φ80. Biotechnology and bioengineering, 116(7), 1820-1826. https://doi.org/10.1002/bit.26971

Llabani, E., Hicklin, R. W., Lee, H. Y., Motika, S. E., Crawford, L. A., Weerapana, E., & Hergenrother, P. (2019). Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis. Nature Chemistry, 11(6), 521-532. https://doi.org/10.1038/s41557-019-0261-6

Aye, Y., & Hergenrother, P. (2019). Editorial overview: From the iceman to modern medicine. Current Opinion in Chemical Biology, 50, A1-A2. https://doi.org/10.1016/j.cbpa.2019.04.021

Hegemann, J. D., Bobeica, S. C., Walker, M. C., Bothwell, I. R., & van der Donk, W. A. (2019). Assessing the Flexibility of the Prochlorosin 2.8 Scaffold for Bioengineering Applications. ACS synthetic biology, 8(5), 1204-1214. https://doi.org/10.1021/acssynbio.9b00080

Hamedirad, M., Weisberg, S., Chao, R., Lian, J., & Zhao, H. (2019). Highly Efficient Single-Pot Scarless Golden Gate Assembly. ACS synthetic biology, 8(5), 1047-1054. https://doi.org/10.1021/acssynbio.8b00480

Sweedler, J. V. (2019). The Periodic Table of Elements at 150. Analytical chemistry, 91(9). https://doi.org/10.1021/acs.analchem.9b01714

Zhu, L., Zou, Q., Cao, X., & Cronan, J. E. (2019). Enterococcus faecalis encodes an atypical auxiliary acyl carrier protein required for efficient regulation of fatty acid synthesis by exogenous fatty acids. mBio, 10(3), [e00577-19]. https://doi.org/10.1128/mBio.00577-19

Srinivas, S., Hu, Z., & Cronan, J. E. (2019). Escherichia coli vectors having stringently repressible replication origins allow a streamlining of Crispr/Cas9 gene editing. Plasmid, 103, 53-62. https://doi.org/10.1016/j.plasmid.2019.04.004

Mothet, J. P., Billard, J. M., Pollegioni, L., Coyle, J. T., & Sweedler, J. V. (2019). Investigating brain d-serine: Advocacy for good practices. Acta Physiologica, 226(1), [e13257]. https://doi.org/10.1111/apha.13257

Neumann, E. K., Comi, T. J., Rubakhin, S., & Sweedler, J. V. (2019). Lipid Heterogeneity between Astrocytes and Neurons Revealed by Single-Cell MALDI-MS Combined with Immunocytochemical Classification. Angewandte Chemie - International Edition, 58(18), 5910-5914. https://doi.org/10.1002/anie.201812892

Petronikolou, N., Ortega, M. A., Borisova, S. A., Nair, S. K., & Metcalf, W. W. (2019). Molecular Basis of Bacillus subtilis ATCC 6633 Self-Resistance to the Phosphono-oligopeptide Antibiotic Rhizocticin. ACS chemical biology, 14(4), 742-750. https://doi.org/10.1021/acschembio.9b00030

Sweedler, J. V. (2019). Advancing the Fields of Measurement Science with Partnerships and Awards. Analytical chemistry, 91(7). https://doi.org/10.1021/acs.analchem.9b01310

Shields, R. C., & Jensen, P. A. (2019). The bare necessities: Uncovering essential and condition-critical genes with transposon sequencing. Molecular Oral Microbiology, 34(2), 39-50. https://doi.org/10.1111/omi.12256

Tang, W., Bobeica, S. C., Wang, L., & van der Donk, W. A. (2019). CylA is a sequence-specific protease involved in toxin biosynthesis. Journal of Industrial Microbiology and Biotechnology, 46(3-4), 537-549. https://doi.org/10.1007/s10295-018-2110-9

Muraglia, K. A., Chorghade, R. S., Kim, B. R., Tang, X. X., Shah, V. S., Grillo, A. S., ... Burke, M. (2019). Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia. Nature, 567(7748), 405-408. https://doi.org/10.1038/s41586-019-1018-5

Wu, C., Biswas, S., Garcia De Gonzalo, C. V., & van der Donk, W. A. (2019). Investigations into the Mechanism of Action of Sublancin. ACS Infectious Diseases, 5(3), 454-459. https://doi.org/10.1021/acsinfecdis.8b00320

Sweedler, J. V. (2019). Salami Publications and Duplicate Submissions: Put Them on Your List of Things to Avoid. Analytical chemistry, 91(5), 3177-3178. https://doi.org/10.1021/acs.analchem.9b00904

Zukher, I., Pavlov, M., Tsibulskaya, D., Kulikovsky, A., Zyubko, T., Bikmetov, D., ... Severinova, K. (2019). Reiterative synthesis by the ribosome and recognition of the N-terminal formyl group by biosynthetic machinery contribute to evolutionary conservation of the length of antibiotic microcin c peptide precursor. mBio, 10(2), [e00768-19]. https://doi.org/10.1128/mBio.00768-19

Sweedler, J. V. (2019). The Evolving World of Scientific Publications: From Unethical Behaviors to New Mandates from Funding Agencies. Analytical Chemistry, 91(3), 1673-1674. https://doi.org/10.1021/acs.analchem.9b00332

Wang, B., Guo, F., Dong, S. H., & Zhao, H. (2019). Activation of silent biosynthetic gene clusters using transcription factor decoys. Nature chemical biology, 15(2), 111-114. https://doi.org/10.1038/s41589-018-0187-0

Aguirre, M. Á., Long, K. D., Canals, A., & Cunningham, B. T. (2019). Point-of-use detection of ascorbic acid using a spectrometric smartphone-based system. Food Chemistry, 272, 141-147. https://doi.org/10.1016/j.foodchem.2018.08.002

Woodburn, E. V., Long, K. D., & Cunningham, B. T. (2019). Analysis of Paper-Based Colorimetric Assays with a Smartphone Spectrometer. IEEE Sensors Journal, 19(2), 508-514. [8494768]. https://doi.org/10.1109/JSEN.2018.2876631

Bobeica, S. C., Dong, S. H., Huo, L., Mazo, N., McLaughlin, M. I., Jiménez-Osés, G., ... van der Donk, W. A. (2019). Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease. eLife, 8. https://doi.org/10.7554/eLife.42305

Bingham, T. W., Hernandez, L. W., Olson, D. G., Svec, R. L., Hergenrother, P., & Sarlah, D. (2019). Enantioselective Synthesis of Isocarbostyril Alkaloids and Analogs Using Catalytic Dearomative Functionalization of Benzene. Journal of the American Chemical Society, 141(1), 657-670. https://doi.org/10.1021/jacs.8b12123

Dicaprio, A. J., Firouzbakht, A., Hudson, G. A., & Mitchell, D. A. (2019). Enzymatic Reconstitution and Biosynthetic Investigation of the Lasso Peptide Fusilassin. Journal of the American Chemical Society, 141(1), 290-297. https://doi.org/10.1021/jacs.8b09928

Zhou, Y., Wei, Y., Lin, L., Xu, T., Ang, E. L., Zhao, H., ... Zhang, Y. (2019). Biochemical and structural investigation of sulfoacetaldehyde reductase from Klebsiella oxytoca. Biochemical Journal, 476(4), 733-746. https://doi.org/10.1042/BCJ20190005

Fu, H., Goettge, M. N., & Metcalf, W. W. (2019). Biochemical characterization of the methylmercaptopropionate: Cob(I)alamin Methyltransferase from Methanosarcina acetivorans. Journal of bacteriology, 201(12), [e00130-19]. https://doi.org/10.1128/JB.00130-19

Mahanta, N., Szantai-Kis, D. M., Petersson, E. J., & Mitchell, D. A. (2019). Biosynthesis and Chemical Applications of Thioamides. ACS chemical biology. https://doi.org/10.1021/acschembio.8b01022

Dong, S. H., Kulikovsky, A., Zukher, I., Estrada, P., Dubiley, S., Severinov, K., & Nair, S. K. (2019). Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor. Chemical Science, 10(8), 2391-2395. https://doi.org/10.1039/C8SC03173H

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Lim, Y. H., Hoon, S., ... Wong, F. T. (2019). Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes. Biotechnology and bioengineering. https://doi.org/10.1002/bit.27021

Nguyen, K., DeSieno, M. A., Bae, B., Johannes, T. W., Cobb, R. E., Zhao, H., & Nair, S. K. (2019). Characterization of the flavin monooxygenase involved in biosynthesis of the antimalarial FR-900098. Organic and Biomolecular Chemistry, 17(6), 1506-1518. https://doi.org/10.1039/c8ob02840k

Shi, S., Liang, Y., Ang, E. L., & Zhao, H. (2019). Delta integration CRISPR-Cas (Di-CRISPR) in saccharomyces cerevisiae. In Methods in Molecular Biology (pp. 73-91). (Methods in Molecular Biology; Vol. 1927). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-9142-6_6

Sabri, L., Huang, Q., Liu, J. N., & Cunningham, B. T. (2019). Design of anapole mode electromagnetic field enhancement structures for biosensing applications. Optics Express, 27(5), 7196-7212. https://doi.org/10.1364/OE.27.007196

Neumann, E. K., Do, T. D., Comi, T. J., & Sweedler, J. V. (2019). Exploring the Fundamental Structures of Life: Non-Targeted, Chemical Analysis of Single Cells and Subcellular Structures. Angewandte Chemie - International Edition. https://doi.org/10.1002/anie.201811951

Schlein, L. J., Fadl-Alla, B., Pondenis, H. C., Lezmi, S., Eberhart, C. G., LeBlanc, A. K., ... Fan, T. M. (2019). Immunohistochemical characterization of procaspase-3 overexpression as a druggable target with PAC-1, a procaspase-3 activator, in canine and human brain cancers. Frontiers in Oncology, 9(FEB), [96]. https://doi.org/10.3389/fonc.2019.00096

Dong, S. H., Liu, A., Mahanta, N., Mitchell, D. A., & Nair, S. K. (2019). Mechanistic Basis for Ribosomal Peptide Backbone Modifications. ACS Central Science. https://doi.org/10.1021/acscentsci.9b00124

Nayak, D. D., & Metcalf, W. W. (2019). Methylamine-specific methyltransferase paralogs in Methanosarcina are functionally distinct despite frequent gene conversion. ISME Journal. https://doi.org/10.1038/s41396-019-0428-6

Bouvier, J. T., Sernova, N. V., Ghasempur, S., Rodionova, I. A., Vetting, M. W., Al-Obaidi, N. F., ... Rodionov, D. A. (2019). Novel metabolic pathways and regulons for hexuronate utilization in Proteobacteria. Journal of bacteriology, 201(2), [e00431-18]. https://doi.org/10.1128/JB.00431-18

Aguirre, M. Á., Long, K. D., & Cunningham, B. T. (2019). Spectrometric Smartphone-Based System for Ibuprofen Quantification in Commercial Dosage Tablets. Journal of Pharmaceutical Sciences. https://doi.org/10.1016/j.xphs.2019.03.010

Jeon, S., Li, Q., Rubakhin, S., Sweedler, J. V., Smith, J. W., Neuringer, M., ... Erdman, J. W. (2019). 13C-lutein is differentially distributed in tissues of an adult female rhesus macaque following a single oral administration: a pilot study. Nutrition Research, 61, 102-108. https://doi.org/10.1016/j.nutres.2018.10.007

Radin, J. N., Zhu, J., Brazel, E. B., McDevitt, C. A., & Kehl-Fie, T. (2019). Synergy between nutritional immunity and independent host defenses contributes to the importance of the MntABC manganese transporter during staphylococcus aureus infection. Infection and immunity, 87(1), [e00642]. https://doi.org/10.1128/IAI.00642-18

Richter, M. F., & Hergenrother, P. (2019). The challenge of converting gram-positive-only compounds into broad-spectrum antibiotics. Annals of the New York Academy of Sciences, 1435(1), 18-38. https://doi.org/10.1111/nyas.13598

Kondakova, T., & Cronan, J. E. (2019). Transcriptional regulation of fatty acid cis–trans isomerization in the solvent-tolerant soil bacterium, Pseudomonas putida F1. Environmental Microbiology. https://doi.org/10.1111/1462-2920.14546

Bougioukou, D. J., Ting, C. P., Peck, S. C., Mukherjee, S., & van der Donk, W. A. (2019). Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin. Organic and Biomolecular Chemistry, 17(4), 822-829. https://doi.org/10.1039/c8ob02860e

Howe, G. W., & van der Donk, W. A. (2018). 18O Kinetic Isotope Effects Reveal an Associative Transition State for Phosphite Dehydrogenase Catalyzed Phosphoryl Transfer. Journal of the American Chemical Society, 140(51), 17820-17824. https://doi.org/10.1021/jacs.8b06301

Rack, J. G. M., Ariza, A., Drown, B. S., Henfrey, C., Bartlett, E., Shirai, T., ... Ahel, I. (2018). (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition. Cell chemical biology, 25(12), 1533-1546.e12. https://doi.org/10.1016/j.chembiol.2018.11.001

Drown, B. S., Shirai, T., Rack, J. G. M., Ahel, I., & Hergenrother, P. (2018). Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chemical Biology, 25(12), 1562-1570.e19. https://doi.org/10.1016/j.chembiol.2018.09.008

Reyes, A. C., Plache, D. C., Koudelka, A. P., Amyes, T. L., Gerlt, J. A., & Richard, J. P. (2018). Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5′-Monophosphate Decarboxylase for Catalysis. Journal of the American Chemical Society, 140(50), 17580-17590. https://doi.org/10.1021/jacs.8b09609

Jeong, H., Moye, L. S., Southey, B. R., Hernandez, A. G., Dripps, I., Romanova, E. V., ... Rodriguez-Zas, S. L. (2018). Gene network dysregulation in the trigeminal ganglia and nucleus accumbens of a model of chronic migraine-associated hyperalgesia. Frontiers in Systems Neuroscience, 12, [63]. https://doi.org/10.3389/fnsys.2018.00063

Singh, R. K., Singh, R., Sivakumar, D., Kondaveeti, S., Kim, T., Li, J., ... Lee, J. K. (2018). Insights into Cell-Free Conversion of CO 2 to Chemicals by a Multienzyme Cascade Reaction ACS Catalysis, 8(12), 11085-11093. https://doi.org/10.1021/acscatal.8b02646

Cronan, J. E. (2018). Advances in synthesis of biotin and assembly of lipoic acid. Current Opinion in Chemical Biology, 47, 60-66. https://doi.org/10.1016/j.cbpa.2018.08.004

Zallot, R., Oberg, N. O., & Gerlt, J. A. (2018). ‘Democratized’ genomic enzymology web tools for functional assignment. Current Opinion in Chemical Biology, 47, 77-85. https://doi.org/10.1016/j.cbpa.2018.09.009

Gerlt, J. A., & Erb, T. J. (2018). Editorial overview: Novel enzymes, coenzymes, and metabolic pathways. Current Opinion in Chemical Biology, 47, A4-A6. https://doi.org/10.1016/j.cbpa.2018.11.008

Tapsin, S., Sun, M., Shen, Y., Zhang, H., Lim, X. N., Susanto, T. T., ... Wan, Y. (2018). Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes. Nature communications, 9(1), [1289]. https://doi.org/10.1038/s41467-018-03675-1

Wang, K. K. A., Ng, T. L., Wang, P., Huang, Z., Balskus, E. P., & van der Donk, W. A. (2018). Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin. Nature communications, 9(1), [3687]. https://doi.org/10.1038/s41467-018-06083-7

Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., ... Zhang, Y. (2018). Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole. Nature communications, 9(1), [4224]. https://doi.org/10.1038/s41467-018-06627-x

Zhuo, Y., Choi, J. S., Marin, T., Yu, H., Harley, B. A., & Cunningham, B. T. (2018). Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM). Light: Science and Applications, 7(1), [7538]. https://doi.org/10.1038/s41377-018-0001-5

Svec, R. L., Furiassi, L., Skibinski, C. G., Fan, T. M., Riggins, G. J., & Hergenrother, P. (2018). Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma. ACS chemical biology, 13(11), 3206-3216. https://doi.org/10.1021/acschembio.8b00864

Svec, R. L., & Hergenrother, P. (2018). Oxygen Starvation Unmasks a Killer. Cell chemical biology, 25(11), 1313-1314. https://doi.org/10.1016/j.chembiol.2018.10.028

Haley, H. M. S., Hill, A. G., Greenwood, A. I., Woerly, E. M., Rienstra, C., & Burke, M. (2018). Peridinin Is an Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation. Journal of the American Chemical Society, 140(45), 15227-15240. https://doi.org/10.1021/jacs.8b06933

Sweedler, J. V. (2018). Science Research - Looking in the Mirror. Analytical chemistry, 90(21), 12323-12324. https://doi.org/10.1021/acs.analchem.8b04786

Rodriguez-Zas, S. L., Wu, C., Southey, B. R., O'Connor, J. C., Nixon, S. E., Garcia, R., ... Dantzer, R. (2018). Disruption of microglia histone acetylation and protein pathways in mice exhibiting inflammation-associated depression-like symptoms. Psychoneuroendocrinology, 97, 47-58. https://doi.org/10.1016/j.psyneuen.2018.06.024

Li, B., Neumann, E. K., Ge, J., Gao, W., Yang, H., Li, P., & Sweedler, J. V. (2018). Interrogation of spatial metabolome of Ginkgo biloba with high-resolution matrix-assisted laser desorption/ionization and laser desorption/ionization mass spectrometry imaging. Plant Cell and Environment, 41(11), 2693-2703. https://doi.org/10.1111/pce.13395

Lian, J., Mishra, S., & Zhao, H. (2018). Recent advances in metabolic engineering of Saccharomyces cerevisiae: New tools and their applications. Metabolic Engineering, 50, 85-108. https://doi.org/10.1016/j.ymben.2018.04.011

Dowd, S. E., Mustroph, M. L., Romanova, E. V., Southey, B. R., Pinardo, H., Rhodes, J. S., & Sweedler, J. V. (2018). Exploring Exercise- and Context-Induced Peptide Changes in Mice by Quantitative Mass Spectrometry. ACS Omega, 3(10), 13817-13827. https://doi.org/10.1021/acsomega.8b01713

Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S., Gillette, M. L., ... Sweedler, J. V. (2018). Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging. Analytical chemistry, 90(19), 11572-11580. https://doi.org/10.1021/acs.analchem.8b02913

Mand, T. D., Kulkarni, G., & Metcalf, W. W. (2018). Genetic, biochemical, and molecular characterization of methanosarcina barkeri mutants lacking three distinct classes of hydrogenase. Journal of bacteriology, 200(20), [e00342]. https://doi.org/10.1128/JB.00342-18

Kelliher, J. L., Radin, J. N., & Kehl-Fie, T. (2018). PhoPR contributes to staphylococcus aureus Growth during phosphate starvation and pathogenesis in an environment- specific manner. Infection and immunity, 86(10), [e00371-18]. https://doi.org/10.1128/IAI.00371-18

Hudson, G. A., & Mitchell, D. A. (2018). RiPP antibiotics: biosynthesis and engineering potential. Current Opinion in Microbiology, 45, 61-69. https://doi.org/10.1016/j.mib.2018.02.010

An, L., Cogan, D. P., Navo, C. D., Jiménez-Osés, G., Nair, S. K., & van der Donk, W. A. (2018). Substrate-assisted enzymatic formation of lysinoalanine in duramycin. Nature chemical biology, 14(10), 928-933. https://doi.org/10.1038/s41589-018-0122-4

Livezey, M., Huang, R., Hergenrother, P., & Shapiro, D. J. (2018). Strong and sustained activation of the anticipatory unfolded protein response induces necrotic cell death. Cell Death and Differentiation, 25(10), 1796-1807. https://doi.org/10.1038/s41418-018-0143-2

Si, T., Tian, Q., Min, Y., Zhang, L., Sweedler, J. V., van der Donk, W. A., & Zhao, H. (2018). Rapid Screening of Lanthipeptide Analogs via In-Colony Removal of Leader Peptides in Escherichia coli. Journal of the American Chemical Society, 140(38), 11884-11888. https://doi.org/10.1021/jacs.8b05544

Tasker, S. Z., Cowfer, A. E., & Hergenrother, P. (2018). Preparation of Structurally Diverse Compounds from the Natural Product Lycorine. Organic Letters, 20(18), 5894-5898. https://doi.org/10.1021/acs.orglett.8b02562

O'Reilly, M. C., Dong, S. H., Rossi, F. M., Karlen, K. M., Kumar, R. S., Nair, S. K., & Blackwell, H. E. (2018). Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop “Out” Conformation for LasR. Cell chemical biology, 25(9), 1128-1139.e3. https://doi.org/10.1016/j.chembiol.2018.06.007

Wang, P., Liang, J., Shi, L. Z., Wang, Y., Zhang, P., Ouyang, M., ... Wang, Y. (2018). Visualizing Spatiotemporal Dynamics of Intercellular Mechanotransmission upon Wounding. ACS Photonics, 5(9), 3565-3574. https://doi.org/10.1021/acsphotonics.8b00383

Kapoor, I., & Nair, S. K. (2018). Structure-Guided Analyses of a Key Enzyme Involved in the Biosynthesis of an Antivitamin. Biochemistry, 57(36), 5282-5288. https://doi.org/10.1021/acs.biochem.8b00576

Sweedler, J. V. (2018). Where Do Our Manuscripts Come From? Analytical chemistry, 90(17). https://doi.org/10.1021/acs.analchem.8b03710

Lian, J., HamediRad, M., & Zhao, H. (2018). Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System. Biotechnology Journal, 13(9), [1700601]. https://doi.org/10.1002/biot.201700601

Fine, J. D., Shpigler, H. Y., Ray, A. M., Beach, N. J., Sankey, A. L., Cash-Ahmed, A., ... Robinson, G. E. (2018). Quantifying the effects of pollen nutrition on honey bee queen egg laying with a new laboratory system. PloS one, 13(9), [e0203444]. https://doi.org/10.1371/journal.pone.0203444

McLaughlin, M. I., & van der Donk, W. A. (2018). Stereospecific Radical-Mediated B12-Dependent Methyl Transfer by the Fosfomycin Biosynthesis Enzyme Fom3. Biochemistry, 57(33), 4967-4971. https://doi.org/10.1021/acs.biochem.8b00616

Lim, Y. H., Wong, F. T., Yeo, W. L., Ching, K. C., Lim, Y. W., Heng, E., ... Zhao, H. (2018). Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation. ChemBioChem, 19(16), 1716-1719. https://doi.org/10.1002/cbic.201800266

Litman, Z. C., Wang, Y., Zhao, H., & Hartwig, J. F. (2018). Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis. Nature, 560(7718), 355-359. https://doi.org/10.1038/s41586-018-0413-7

Peh, J., Boudreau, M. W., Smith, H. M., & Hergenrother, P. (2018). Overcoming Resistance to Targeted Anticancer Therapies through Small-Molecule-Mediated MEK Degradation. Cell chemical biology, 25(8), 996-1005.e4. https://doi.org/10.1016/j.chembiol.2018.05.008

Romanova, E. V., & Sweedler, J. V. (2018). Animal Model Systems in Neuroscience. ACS Chemical Neuroscience, 9(8), 1869-1870. https://doi.org/10.1021/acschemneuro.8b00380

Green, D. J., Huang, R. C., Sudlow, L., Hatcher, N., Potgieter, K., McCrohan, C., ... Gillette, R. (2018). CAMP, Ca2+, pHi, and NO Regulate H-like Cation Channels That Underlie Feeding and Locomotion in the Predatory Sea Slug Pleurobranchaea californica. ACS Chemical Neuroscience, 9(8), 1986-1993. https://doi.org/10.1021/acschemneuro.8b00187

Atkins, N., Ren, S., Hatcher, N., Burgoon, P. W., Mitchell, J. W., Sweedler, J. V., & Gillette, M. L. (2018). Functional Peptidomics: Stimulus- and Time-of-Day-Specific Peptide Release in the Mammalian Circadian Clock. ACS Chemical Neuroscience, 9(8), 2001-2008. https://doi.org/10.1021/acschemneuro.8b00089

Zhang, G., Yuan, W. D., Vilim, F. S., Romanova, E. V., Yu, K., Yin, S. Y., ... Jing, J. (2018). Newly Identified Aplysia SPTR-Gene Family-Derived Peptides: Localization and Function. ACS Chemical Neuroscience, 9(8), 2041-2053. https://doi.org/10.1021/acschemneuro.7b00513

Sweedler, J. V. (2018). Where Is the Data? Analytical chemistry, 90(15). https://doi.org/10.1021/acs.analchem.8b03212

Schwalen, C. J., Hudson, G. A., Kille, B., & Mitchell, D. A. (2018). Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics. Journal of the American Chemical Society, 140(30), 9494-9501. https://doi.org/10.1021/jacs.8b03896

Sales, M. J., Herbert, W. G., Du, Y., Sandur, A. S., Stanley, N. M., & Jensen, P. A. (2018). Complete genome sequences of streptococcus sobrinus SL1 (ATCC 33478 DSM 20742), NIDR 6715-7 (ATCC 27351), NIDR 6715-15 (ATCC 27352), and NCTC 10919 (ATCC 33402). Microbiology Resource Announcements, 7(3), [e00804-18]. https://doi.org/10.1128/MRA.00804-18

Cao, X., Zhu, L., Song, X., Hu, Z., & Cronan, J. E. (2018). Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes. Proceedings of the National Academy of Sciences of the United States of America, 115(30), E7063-E7072. https://doi.org/10.1073/pnas.1805862115

Gerlt, J. A. (2018). The Need for Manuscripts to Include Database Identifiers for Proteins. Biochemistry, 57(29), 4239-4240. https://doi.org/10.1021/acs.biochem.8b00705

Cao, X., Koch, T., Steffens, L., Finkensieper, J., Zigann, R., Cronan, J. E., & Dahl, C. (2018). Lipoate-binding proteins and specific lipoate-protein ligases in microbial sulfur oxidation reveal an atpyical role for an old cofactor. eLife, 7, [e37439]. https://doi.org/10.7554/eLife.37439

Petronikolou, N., & Nair, S. K. (2018). Structural and Biochemical Studies of a Biocatalyst for the Enzymatic Production of Wax Esters. ACS Catalysis, 8(7), 6334-6344. https://doi.org/10.1021/acscatal.8b00787

Movassaghi, M., & van der Donk, W. A. (2018). Synthesis of Antibiotics and Related Molecules. Journal of Organic Chemistry, 83(13), 6826-6828. https://doi.org/10.1021/acs.joc.8b01330

Estrada, P., Morita, M., Hao, Y., Schmidt, E. W., & Nair, S. K. (2018). A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases. Journal of the American Chemical Society, 140(26), 8124-8127. https://doi.org/10.1021/jacs.8b05187

Weir, W. B., Fred, L. Y., Pike, M., Rubakhin, S., Ludwig, T. J., Shar, A. M., ... Sweedler, J. V. (2018). Expired Epinephrine Maintains Chemical Concentration and Sterility. Prehospital Emergency Care, 22(4), 414-418. https://doi.org/10.1080/10903127.2017.1402109

Kulkarni, G., Mand, T. D., & Metcalf, W. W. (2018). Energy conservation via hydrogen cycling in the methanogenic archaeon Methanosarcina barkeri. mBio, 9(4), [e01256-18]. https://doi.org/10.1128/mBio.01256-18

Carter, M. S., Zhang, X., Huang, H., Bouvier, J. T., Francisco, B. S., Vetting, M. W., ... Gerlt, J. A. (2018). Functional assignment of multiple catabolic pathways for d-apiose article. Nature chemical biology, 14(7), 696-705. https://doi.org/10.1038/s41589-018-0067-7

Bao, Z., HamediRad, M., Xue, P., Xiao, H., Tasan, I., Chao, R., ... Zhao, H. (2018). Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision. Nature Biotechnology, 36(6), 505-508. https://doi.org/10.1038/nbt.4132

Shi, S., Ang, E. L., & Zhao, H. (2018). In vivo biosensors: mechanisms, development, and applications. Journal of Industrial Microbiology and Biotechnology, 45(7), 491-516. https://doi.org/10.1007/s10295-018-2004-x

Katz, L., Chen, Y. Y., Gonzalez, R., Peterson, T. C., Zhao, H., & Baltz, R. H. (2018). Synthetic biology advances and applications in the biotechnology industry: a perspective. Journal of Industrial Microbiology and Biotechnology, 45(7), 449-461. https://doi.org/10.1007/s10295-018-2056-y

Shen, M., Qu, Z., Deslaurier, J., Welle, T. M., Sweedler, J. V., & Chen, R. (2018). Single Synaptic Observation of Cholinergic Neurotransmission on Living Neurons: Concentration and Dynamics. Journal of the American Chemical Society, 140(25), 7764-7768. https://doi.org/10.1021/jacs.8b01989

Drown, B. S., & Hergenrother, P. (2018). Going on offense against the gram-negative defense. Proceedings of the National Academy of Sciences of the United States of America, 115(26), 6530-6532. https://doi.org/10.1073/pnas.1807278115

Ongpipattanakul, C., & Nair, S. K. (2018). Biosynthetic Proteases That Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides. Biochemistry, 57(23), 3201-3209. https://doi.org/10.1021/acs.biochem.8b00114

Li, B., Dunham, S. J. B., Ellis, J. F., Lange, J. D., Smith, J. R., Yang, N., ... Sweedler, J. V. (2018). A Versatile Strategy for Characterization and Imaging of Drip Flow Microbial Biofilms. Analytical chemistry, 90(11), 6725-6734. https://doi.org/10.1021/acs.analchem.8b00560

Gerlt, J. A. (2018). Special Issue: Current Topics in Mechanistic Enzymology. Biochemistry, 57(22), 3085-3086. https://doi.org/10.1021/acs.biochem.8b00585

Aguirre, M. Á., Long, K. D., Li, N., Manoto, S. L., & Cunningham, B. T. (2018). Detection and digital resolution counting of nanoparticles with optical resonators and applications in biosensing. Chemosensors, 6(2), [13]. https://doi.org/10.3390/chemosensors6020013

Lian, J., Bao, Z., Hu, S., & Zhao, H. (2018). Engineered CRISPR/Cas9 system for multiplex genome engineering of polyploid industrial yeast strains. Biotechnology and bioengineering, 115(6), 1630-1635. https://doi.org/10.1002/bit.26569

HamediRad, M., Lian, J., Li, H., & Zhao, H. (2018). RNAi assisted genome evolution unveils yeast mutants with improved xylose utilization. Biotechnology and bioengineering, 115(6), 1552-1560. https://doi.org/10.1002/bit.26570

Do, T. D., Ellis, J. F., Neumann, E. K., Comi, T. J., Tillmaand, E. G., Lenhart, A. E., ... Sweedler, J. V. (2018). Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins. ChemPhysChem, 19(10), 1180-1191. https://doi.org/10.1002/cphc.201701364

Checco, J. W., Zhang, G., Yuan, W. D., Yu, K., Yin, S. Y., Roberts-Galbraith, R. H., ... Sweedler, J. V. (2018). Molecular and Physiological Characterization of a Receptor for d -Amino Acid-Containing Neuropeptides. ACS chemical biology, 13(5), 1343-1352. https://doi.org/10.1021/acschembio.8b00167

Morita, M., Hao, Y., Jokela, J. K., Sardar, D., Lin, Z., Sivonen, K., ... Schmidt, E. W. (2018). Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis. Journal of the American Chemical Society, 140(19), 6044-6048. https://doi.org/10.1021/jacs.8b03137

Anapindi, K. D. B., Romanova, E. V., Southey, B. R., & Sweedler, J. V. (2018). Peptide identifications and false discovery rates using different mass spectrometry platforms. Talanta, 182, 456-463. https://doi.org/10.1016/j.talanta.2018.01.062

Hegemann, J. D., & van der Donk, W. A. (2018). Investigation of Substrate Recognition and Biosynthesis in Class IV Lanthipeptide Systems. Journal of the American Chemical Society, 140(17), 5743-5754. https://doi.org/10.1021/jacs.8b01323

Sweedler, J. V. (2018). A Resource for Our Reagents: ACS Reagent Chemicals. Analytical Chemistry, 90(9). https://doi.org/10.1021/acs.analchem.8b01729

Li, L., Andrén, P. E., & Sweedler, J. V. (2018). Editorial and Review: 29th ASMS Sanibel Conference on Mass Spectrometry—Peptidomics: Bridging the Gap between Proteomics and Metabolomics by MS. Journal of the American Society for Mass Spectrometry, 29(5), 801-806. https://doi.org/10.1007/s13361-018-1939-5

Monroe, E. B., Annangudi, S. P., Wadhams, A. A., Richmond, T. A., Yang, N., Southey, B. R., ... Sweedler, J. V. (2018). Exploring the Sea Urchin Neuropeptide Landscape by Mass Spectrometry. Journal of the American Society for Mass Spectrometry, 29(5), 923-934. https://doi.org/10.1007/s13361-018-1898-x

Hu, Z., Dong, H., Ma, J. C., Yu, Y., Li, K. H., Guo, Q. Q., ... Wang, H. (2018). Novel Xanthomonas campestris long-chain-specific 3-oxoacyl- acyl carrier protein reductase involved in diffusible signal factor synthesis. mBio, 9(3), [e00596-18]. https://doi.org/10.1128/mBio.00596-18

Dunham, S. J. B., Ellis, J. F., Baig, N. F., Morales-Soto, N., Cao, T., Shrout, J. D., ... Sweedler, J. V. (2018). Quantitative SIMS Imaging of Agar-Based Microbial Communities. Analytical chemistry, 90(9), 5654-5663. https://doi.org/10.1021/acs.analchem.7b05180

Greenwood, M. P., Greenwood, M., Romanova, E. V., Mecawi, A. S., Paterson, A., Sarenac, O., ... Murphy, D. (2018). The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system. Neurobiology of Aging, 65, 178-191. https://doi.org/10.1016/j.neurobiolaging.2018.01.008

Hetrick, K. J., Walker, M. C., & van der Donk, W. A. (2018). Development and Application of Yeast and Phage Display of Diverse Lanthipeptides. ACS Central Science, 4(4), 458-467. https://doi.org/10.1021/acscentsci.7b00581

Parkinson, E. I., Tryon, J. H., Goering, A. W., Ju, K. S., McClure, R. A., Kemball, J. D., ... Metcalf, W. W. (2018). Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics. ACS chemical biology, 13(4), 1029-1037. https://doi.org/10.1021/acschembio.7b01089

Kakkar, N., Perez, J. G., Liu, W. R., Jewett, M. C., & van der Donk, W. A. (2018). Incorporation of Nonproteinogenic Amino Acids in Class i and II Lantibiotics. ACS chemical biology, 13(4), 951-957. https://doi.org/10.1021/acschembio.7b01024

Limsakul, P., Peng, Q., Wu, Y., Allen, M. E., Liang, J., Remacle, A. G., ... Wang, Y. (2018). Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface. Cell chemical biology, 25(4), 370-379.e4. https://doi.org/10.1016/j.chembiol.2018.01.002

Petronikolou, N., Hollatz, A. J., Schuler, M. A., & Nair, S. K. (2018). Loganic Acid Methyltransferase: Insights into the Specificity of Methylation on an Iridoid Glycoside. ChemBioChem, 19(8), 784-788. https://doi.org/10.1002/cbic.201700679

Trobe, M., & Burke, M. (2018). The Molecular Industrial Revolution: Automated Synthesis of Small Molecules. Angewandte Chemie - International Edition, 57(16), 4192-4214. https://doi.org/10.1002/anie.201710482

Yang, N., Anapindi, K. D. B., Rubakhin, S., Wei, P., Yu, Q., Li, L., ... Sweedler, J. V. (2018). Neuropeptidomics of the Rat Habenular Nuclei. Journal of Proteome Research, 17(4), 1463-1473. https://doi.org/10.1021/acs.jproteome.7b00811

Yang, X., Lennard, K. R., He, C., Walker, M. C., Ball, A. T., Doigneaux, C., ... van der Donk, W. A. (2018). A lanthipeptide library used to identify a protein-protein interaction inhibitor article. Nature chemical biology, 14(4), 375-380. https://doi.org/10.1038/s41589-018-0008-5

Sun, H., Zhang, H., Ang, E. L., & Zhao, H. (2018). Biocatalysis for the synthesis of pharmaceuticals and pharmaceutical intermediates. Bioorganic and Medicinal Chemistry, 26(7), 1275-1284. https://doi.org/10.1016/j.bmc.2017.06.043

Wei, Y., Ang, E. L., & Zhao, H. (2018). Recent developments in the application of P450 based biocatalysts. Current Opinion in Chemical Biology, 43, 1-7. https://doi.org/10.1016/j.cbpa.2017.08.006

Della Ripa, L. A., Petros, Z. A., Cioffi, A. G., Piehl, D. W., Courtney, J. M., Burke, M. D., & Rienstra, C. M. (2018). Solid-State NMR of highly 13 C-enriched cholesterol in lipid bilayers Methods, 138-139, 47-53. https://doi.org/10.1016/j.ymeth.2018.01.008

Repka, L. M., Hetrick, K. J., Chee, S. H., & van der Donk, W. A. (2018). Characterization of Leader Peptide Binding during Catalysis by the Nisin Dehydratase NisB. Journal of the American Chemical Society, 140(12), 4200-4203. https://doi.org/10.1021/jacs.7b13506

Mahanta, N., Liu, A., Dong, S., Nair, S. K., & Mitchell, D. A. (2018). Enzymatic reconstitution of ribosomal peptide backbone thioamidation. Proceedings of the National Academy of Sciences of the United States of America, 115(12), 3030-3035. https://doi.org/10.1073/pnas.1722324115

Davis, R. G., Park, H. M., Kim, K., Greer, J. B., Fellers, R. T., Leduc, R. D., ... Kelleher, N. L. (2018). Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms between Mouse Strains. Analytical chemistry, 90(6), 3802-3810. https://doi.org/10.1021/acs.analchem.7b04108

Ulrich, E. C., Bougioukou, D. J., & van der Donk, W. A. (2018). Investigation of Amide Bond Formation during Dehydrophos Biosynthesis. ACS chemical biology, 13(3), 537-541. https://doi.org/10.1021/acschembio.7b00949

Eriksen, D. T., Chao, R., & Zhao, H. (2018). Applying advanced dna assembly methods to generate pathway libraries. In Synthetic Biology: Parts, Devices and Applications (pp. 331-347). Wiley-VCH Verlag. https://doi.org/10.1002/9783527688104.ch16

Sweedler, J. V. (2018). Who Are Your Coauthors? Make Sure to Follow Appropriate Practices. Analytical chemistry, 90(5), 2977-2978. https://doi.org/10.1021/acs.analchem.8b00785

Wang, Y., Ren, H., & Zhao, H. (2018). Expanding the boundary of biocatalysis: design and optimization of in vitro tandem catalytic reactions for biochemical production. Critical Reviews in Biochemistry and Molecular Biology, 53(2), 115-129. https://doi.org/10.1080/10409238.2018.1431201

Sweedler, J. V. (2018). The ACS Measurement Journals, the Analytical Division, and Pittcon 2018: A Busy Four Days. Analytical chemistry, 90(4). https://doi.org/10.1021/acs.analchem.8b00575

Race, C. M., Kwon, L. E., Foreman, M. T., Huang, Q., Inan, H., Kesiraju, S., ... Cunningham, B. T. (2018). An Automated Microfluidic Assay for Photonic Crystal Enhanced Detection and Analysis of an Antiviral Antibody Cancer Biomarker in Serum. IEEE Sensors Journal, 18(4), 1464-1473. [8119803]. https://doi.org/10.1109/JSEN.2017.2777529

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., ... Zhang, B. (2018). How many human proteoforms are there? Nature chemical biology, 14(3), 206-214. https://doi.org/10.1038/nchembio.2576

Liu, J. N., Huang, Q., Liu, K. K., Singamaneni, S., & Cunningham, B. T. (2018). Nanoantenna-microcavity hybrid resonators with highly cooperative plasmonic-photonic coupling. In 2017 IEEE Photonics Conference (IPC) Part II (Vol. 2018-January, pp. 1-2). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/PC2.2017.8283406

Wan, Y., Carlson, J. A., Al-Mulla, S. A., Peng, W., Long, K. D., Kesler, B. A., ... Cunningham, B. T. (2018). Integrated spectroscopic analysis system with low vertical height for measuring liquid or solid assays. Sensors and Actuators, B: Chemical, 255, 935-943. https://doi.org/10.1016/j.snb.2017.08.126

Besold, A. N., Gilston, B. A., Radin, J. N., Ramsoomair, C., Culbertson, E. M., Li, C. X., ... Culotta, V. C. (2018). Role of calprotectin in withholding zinc and copper from Candida albicans. Infection and immunity, 86(2), [e00779-17]. https://doi.org/10.1128/IAI.00779-17

Calhoun, S., Korczynska, M., Wichelecki, D. J., San Francisco, B., Zhao, S., Rodionov, D. A., ... Sali, A. (2018). Prediction of enzymatic pathways by integrative pathway mapping. eLife, 7, [e31097]. https://doi.org/10.7554/eLife.31097

Cao, X., Hong, Y., Zhu, L., Hu, Y., & Cronan, J. E. (2018). Development and retention of a primordial moonlighting pathway of protein modification in the absence of selection presents a puzzle. Proceedings of the National Academy of Sciences of the United States of America, 115(4), 647-655. https://doi.org/10.1073/pnas.1718653115

Qi, M., Philip, M. C., Yang, N., & Sweedler, J. V. (2018). Single Cell Neurometabolomics. ACS Chemical Neuroscience, 9(1), 40-50. https://doi.org/10.1021/acschemneuro.7b00304

Cunningham, B. T., Long, K. D., Yu, H., Chen, W., Sun, F., Ornob, A., ... Bashir, R. (2018). Mobile biosensing using the sensing capabilities of smartphone cameras. In 2017 IEEE MTT-S International Microwave Workshop Series on Advanced Materials and Processes for RF and THz Applications, IMWS-AMP 2017 (pp. 1-3). (2017 IEEE MTT-S International Microwave Workshop Series on Advanced Materials and Processes for RF and THz Applications, IMWS-AMP 2017; Vol. 2018-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IMWS-AMP.2017.8247439

Manandhar, M., & Cronan, J. E. (2018). A canonical biotin synthesis enzyme, 8-amino-7- oxononanoate synthase (BioF), utilizes different acyl chain donors in Bacillus subtilis and Escherichia coli. Applied and environmental microbiology, 84(1), [e02084-17]. https://doi.org/10.1128/AEM.02084-17

Sun, H., Zhao, H., & Ang, E. L. (2018). A coupled chlorinase-fluorinase system with a high efficiency of trans -halogenation and a shared substrate tolerance. Chemical Communications, 54(68), 9458-9461. https://doi.org/10.1039/c8cc04436h

Kelliher, J. L., Radin, J. N., Grim, K. P., Solórzano, P. K. P., Degnan, P., & Kehl-Fie, T. (2018). Acquisition of the phosphate transporter NptA enhances Staphylococcus aureus pathogenesis by improving phosphate uptake in divergent environments. Infection and immunity, 86(1), [e00631-17]. https://doi.org/10.1128/IAI.00631-17

Welle, T. M., Alanis, K., Colombo, M. L., Sweedler, J. V., & Shen, M. (2018). A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes. Chemical Science, 9(22), 4937-4941. https://doi.org/10.1039/c8sc01131a

Checco, J. W., Zhang, G., Yuan, W. D., Le, Z. W., Jing, J., & Sweedler, J. V. (2018). Aplysia allatotropin-related peptide and its newly identified D-amino acid-containing epimer both activate a receptor and a neuronal target. Journal of Biological Chemistry, 293(43), 16862-16873. https://doi.org/10.1074/jbc.RA118.004367

Southey, B. R., Romanova, E. V., Rodriguez-Zas, S. L., & Sweedler, J. V. (2018). Bioinformatics for prohormone and neuropeptide discovery. In Methods in Molecular Biology (pp. 71-96). (Methods in Molecular Biology; Vol. 1719). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-7537-2_5

Do, T. D., Checco, J. W., Tro, M., Shea, J. E., Bowers, M. T., & Sweedler, J. V. (2018). Conformational investigation of the structure-activity relationship of GdFFD and its analogues on an achatin-like neuropeptide receptor of: Aplysia californica involved in the feeding circuit. Physical Chemistry Chemical Physics, 20(34), 22047-22057. https://doi.org/10.1039/c8cp03661f

Jensen, P. A. (2018). Coupling fluxes, enzymes, and regulation in genome-scale metabolic models. In Methods in Molecular Biology (pp. 337-351). (Methods in Molecular Biology; Vol. 1716). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-7528-0_15

Tasan, I., Sustackova, G., Zhang, L., Kim, J., Sivaguru, M., HamediRad, M., ... Zhao, H. (2018). CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci. Nucleic acids research, 46(17), [e100]. https://doi.org/10.1093/nar/gky501

Storm, A. J., & Jensen, P. A. (2018). Designing Randomized DNA Sequences Free of Restriction Enzyme Recognition Sites. Biotechnology Journal, 13(1), [1700326]. https://doi.org/10.1002/biot.201700326

Hegemann, J. D., Schwalen, C. J., Mitchell, D. A., & van der Donk, W. A. (2018). Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin. Chemical Communications, 54(65), 9007-9010. https://doi.org/10.1039/c8cc04411b

Yien, Y. Y., Shi, J., Chen, C., Cheung, J. T. M., Grillo, A. S., Shrestha, R., ... Paw, B. H. (2018). FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. Journal of Biological Chemistry, 293(51), 19797-19811. https://doi.org/10.1074/jbc.RA118.002742

Nayak, D. D., & Metcalf, W. W. (2018). Genetic techniques for studies of methyl-coenzyme M reductase from Methanosarcina acetivorans C2A. In F. Armstrong (Ed.), Methods in Enzymology (pp. 325-347). (Methods in Enzymology; Vol. 613). Academic Press Inc.. https://doi.org/10.1016/bs.mie.2018.10.012

Dutta, D., Lai, K. Y., Reyes-Ordoñez, A., Chen, J., & van der Donk, W. A. (2018). Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. Journal of Lipid Research, 59(8), 1433-1445. https://doi.org/10.1194/jlr.M085274

Schultz, C., Lian, J., & Zhao, H. (Accepted/In press). Metabolic Engineering of Saccharomyces cerevisiae Using a Trifunctional CRISPR/Cas System for Simultaneous Gene Activation, Interference, and Deletion. Methods in Enzymology. https://doi.org/10.1016/bs.mie.2018.04.010

Ongpipattanakul, C., & Nair, S. K. (Accepted/In press). Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis. ACS Chemical Biology. https://doi.org/10.1021/acschembio.8b00668

Tai, H. C., Checco, J. W., & Sweedler, J. V. (2018). Non-targeted identification of d-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis, and LC-MS. In Methods in Molecular Biology (pp. 107-118). (Methods in Molecular Biology; Vol. 1719). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-7537-2_7

Garcia-Ruiz, E., HamediRad, M., & Zhao, H. (2018). Pathway design, engineering, and optimization. In Advances in Biochemical Engineering/Biotechnology (Advances in Biochemical Engineering/Biotechnology; Vol. 162). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/10_2016_12

Goettge, M. N., Cioni, J. P., Ju, K. S., Pallitsch, K., & Metcalf, W. W. (2018). PcxL and HpxL are flavin-dependent, oxime-forming N-oxidases in phosphonocystoximic acid biosynthesis in Streptomyces. Journal of Biological Chemistry, 293(18), 6859-6868. https://doi.org/10.1074/jbc.RA118.001721

Cunningham, B. T., Liu, J. N., Huang, Q., Canady, T., Long, K. D., Li, N., ... Singamaneni, S. (2018). Photonic crystal resonant coupling to nanoantennas and applications for digital resolution biosensing. In Microscopy Histopathology and Analytics, MICROSCOPY 2018 (Vol. Part F89-MICROSCOPY 2018). OSA - The Optical Society. https://doi.org/10.1364/MICROSCOPY.2018.MW2A.3

Zhuo, Y., Choi, J. S., Marin, T., Yu, H., Harley, B. A., & Cunningham, B. T. (2018). Photonic resonator outcoupler microscopy (PROM) for quantitative monitoring of stem cell focal adhesion area. In Frontiers in Optics, FIO 2018 (Vol. Part F114-FIO 2018). OSA - The Optical Society. https://doi.org/10.1364/FIO.2018.JTu3A.119

Ren, H., Biswas, S., Ho, S., van der Donk, W. A., & Zhao, H. (Accepted/In press). Rapid Discovery of Glycocins through Pathway Refactoring in Escherichia coli. ACS Chemical Biology. https://doi.org/10.1021/acschembio.8b00599

Liu, J. N., Huang, Q., Liu, K. K., Singamaneni, S., & Cunningham, B. T. (2018). Resonant coupling from photonic crystal surfaces to plasmonic nanoantennas: Principles, detection instruments, and applications in digital resolution biosensing. In S. He, E-H. Lee, & S. He (Eds.), Smart Photonic and Optoelectronic Integrated Circuits XX (Vol. 10536). [105361O] SPIE. https://doi.org/10.1117/12.2285828

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Morales-Soto, N., Dunham, S. J. B., Baig, N. F., Ellis, J. F., Madukoma, C. S., Bohn, P. W., ... Shrout, J. D. (2018). Spatially dependent alkyl quinolone signaling responses to antibiotics in Pseudomonas aeruginosa swarms. Journal of Biological Chemistry, 293(24), 9544-9552. https://doi.org/10.1074/jbc.RA118.002605

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