Introduction

Our laboratory is focused on creating biomedical and life sciences experimental models through comparative genomics. We are developing technology platforms and biological models for the life science community to resolve complex traits and diseases. Comparative genomics allows us to capture the genetic basis for a phenotype (trait or disease) across species (from fruit flies, worms, mice, and pigs to man). Thus, our laboratory has focused on the following specific aims:

1. Creating comparative genomics information to exploit biological information across species
2. Creating technological platforms to permit the identification and utilization of genetic diversity
3. Creating biological platforms (cell lines, tissues and animals) to elicit regulatory pathways associated with stem cell differentiation, development and disease.