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New approach enhances muscle recovery in aged mice

April 11, 2022

Scientists have developed a promising new method to combat the age-related losses in muscle mass that often accompany immobility after injury or illness. Their technique, demonstrated in mice, arrests the process by which muscles begin to deteriorate at the onset of exercise after a period of inactivity.

They report their findings in the Journal of Physiology.


April 11, 2022


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Nanostimulators boost stem cells for muscle repair

May 1, 2020

In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

In a new study published in the journal ACS Nano, researchers at the University of Illinois at Urbana-Champaign demonstrated that “nanostimulators” – nanoparticles seeded with a molecule the body naturally produces to prompt stem cells to heal wounds – can amp up stem cells’ regenerative powers in a targeted limb in mice.


May 1, 2020


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Injections, exercise promote muscle regrowth after atrophy in mice

April 29, 2019

By injecting cells that support blood vessel growth into muscles depleted by inactivity, researchers say they are able to help restore muscle mass lost as a result of immobility.

The research, conducted in adult mice, involved injections of cells called pericytes (PERRY-sites), which are known to promote blood vessel growth and dilation in tissues throughout the body. The injections occurred at the end of a two-week period during which the mice were prevented from contracting the muscles in one of their hind legs.


April 29, 2019


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