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Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials

November 21, 2023

Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75% of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these advanced tumors.


November 21, 2023


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New insight into crosstalk between cancer cells and their environment

September 18, 2023

Most solid tumors become stiff as the cancer progresses. Although researchers recognize that the environment around the cancer cells influences their behavior, it is unclear how it does so. In a new paper, published in Scientific Data, researchers from the University of Illinois Urbana-Champaign have collected gene expression data in response to mechanical stiffness in tumors. Their work can help guide our understanding of the crosstalk between cancer cells and their surroundings.


September 18, 2023


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ER-positive breast cancer presents differing metabolic signatures in African American, white women

September 11, 2023

September 11, 2023


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CAR-T immune therapy attacks ovarian cancer in mice with a single dose

August 1, 2023

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor cancer that has eluded such therapies until now. 


August 1, 2023


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Team identifies key driver of cancer cell death pathway that activates immune cells

July 31, 2023

Scientists have identified a protein that plays a critical role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers. They report their findings in the journal Cancer Research


July 31, 2023


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