Skip to main content

Illinois IGB

drug discovery

New approach drives bacteria to produce potential antibiotic, antiparasitic compounds

June 26, 2020

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches. The scientists report their findings in the journal eLife.


June 26, 2020


Related Articles

Study yields million-plus new compounds, pharmaceutical potential

March 12, 2018

Researchers say they can now produce a vast library of unique cyclic compounds, some with the capacity to interrupt specific protein-protein interactions that play a role in disease. The new compounds have cyclic structures that give them stability and enhance their ability to bind to their targets.  

The study, reported in the journal Nature Chemical Biology, also revealed that one of the newly generated compounds interferes with the binding of an HIV protein to a human protein, an interaction vital to the virus’s life cycle.


March 12, 2018


Related Articles

Subscribe to drug discovery