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Auinash Kalsotra

Exploring RNA Splicing’s Role in Liver Cancer

August 19, 2021

When Auinash Kalsotra (CGD/GNDP), member of the Cancer Center at Illinois, Associate Professor and the William C. Rose Scholar of Biochemistry, attended college at Birla Institute of Technology and Science in India, he knew he wanted to pursue an entrepreneurial career inspired by his family members. Instead of following a traditional business route, Kalsotra’s enterprising genes have led him down a trailblazing scientific journey – uncovering intricacies of cell biological mechanisms that may lead to more targeted and improved cancer therapies.


August 19, 2021


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Division of labor within regenerating liver maintains metabolism, mouse study finds

February 27, 2021

The liver has a rare superpower among body organs – the ability to regenerate, even if 70% of its mass is removed. It also keeps up its metabolic and toxin-removing work during the process of regeneration, thanks to a subset of cells that expand their workload while the rest focus on multiplication, a new study in mice found.


February 27, 2021


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Team deciphers how myotonic dystrophy generates lethal heart dysfunctions

February 28, 2020

Roughly 80% of people with myotonic dystrophy – a common form of muscular dystrophy – experience dangerous heart ailments, and heart rhythm defects are the second-leading cause of death in those with the condition. In a new study, researchers traced the molecular events that lead to heart abnormalities in myotonic dystrophy and recreated the disease in a mouse model.

They report their findings in the journal Developmental Cell.


February 28, 2020


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Study identifies key player in heart enlargement

June 27, 2017

The heart is a dynamic muscle that grows and shrinks in response to stressors such as exercise and disease. The secret to its malleability lies in individual cells, which get bigger or smaller depending on the heart’s needs. A new study of mouse hearts reveals a previously unknown mechanism by which heart cells control their size by ramping up or stopping the production of a key factor called PABPC1.


June 27, 2017


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Scientists uncover mechanism that propels liver dev. after birth

November 5, 2015

Any expectant mother will tell you that she wants her baby's organs to develop properly in the womb.

What she may not realize, however, is that a child's internal organs continue to develop for months and years after birth. This critical period is full of cellular changes that transform the organization and function of most tissues. But the exact mechanisms underlying postnatal organ maturation are still a mystery.


November 5, 2015


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