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Mining for anti-infectious Molecules from Genomes

The Mining for anti-infectious Molecules from Genomes theme identifies undiscovered microbial sources with medical potential for new antibiotics and other beneficial drugs and investigates the use of antibody-based strategies against avian influenza.

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Illinois biochemistry professor Satish Nair and his colleagues discovered a new class of DNA-protein hybrids and determined the mechanisms by which they are formed in bacterial cells. The findings will speed the process of finding and developing new DNA-protein hybrid molecules for therapeutic use.
Chemical and biomolecular engineering professor Huimin Zhao will lead a National Science Foundation iBioFoundry at the University of Illinois Urbana-Champaign.
Illinois researchers have opened up the AI "black box" to gain valuable new insight about chemistry for solar energy applications. Pictured, from left: Professor Charles Schroeder, graduate students Changhyun Hwang and Seungjoo Yi, professor Ying Diao, professor Nick Jackson and graduate student Tiara Torres Flores.
Entomology professor Esther Ngumbi studies how two varieties of tomato plants and tobacco hornworm larvae respond to flooding. The hornworm caterpillars are enclosed in plastic bags affixed to the tomato plants.
Researchers in the lab  Inspired by the evolution of some of the earliest lifeforms, University of Illinois professor Angad Mehta, left, Yang-Le Gao and Bidhan De led a proof-of-concept study verifying that natural metabolic processes within cyanobacteria-yeast hybrids can be bioengineered to produce important hydrocarbons and pharmaceutical precursors.
from left, Postdoc Yujie Yuan, Postdoc Zhengyi Zhang, CABBI Conversion Theme Leader Huimin Zhao (seated), Ph.D. Candidate Wesley Harrison, and  Postdoc Maolin Li.