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Mining for anti-infectious Molecules from Genomes

The Mining for anti-infectious Molecules from Genomes theme identifies undiscovered microbial sources with medical potential for new antibiotics and other beneficial drugs and investigates the use of antibody-based strategies against avian influenza.

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Twelve Illinois scientists rank among world's most influential
In human breast cancer cells treated with the preclinical drug ErSO (shown), or with doxorubicin, the cellular protein FGD3 causes another protein, calreticulin (in red on the right), to display on the cancer cell surface, attracting and activating immune cells. Micrographs by Junyao Zhu
EZSpecificity combines extensive new enzyme-substrate docking data and a new machine learning algorithm to predict the best pairing for making a desired product, with up to 91.7% accuracy. Illinois professor Huimin Zhao led the study
Left image: First author of the study Xuenan Mi received an award in 2024 for her work on LassoESM. Right image: Professor Doug Mitchell, Professor Diwakar Shukla, and Susanna Barrett
Chemical and biomolecular engineering professor Huimin Zhao leads the new National Science Foundation iBioFoundry at the University of Illinois Urbana-Champaign. Photo by Michelle Hassel
Bioeconomy U: How Illinois is leading the bio-revolution