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Illinois IGB

Timothy Fan

Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials

November 21, 2023

Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75% of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these advanced tumors.


November 21, 2023


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New antifungal molecule shows ability to kill fungi without toxicity in human cells, mice

November 6, 2023

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug’s power against fungal infections while doing away with its toxicity, report researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison. They reported their findings in the journal Nature.


November 6, 2023


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Three IGB members assume new Cancer Center at Illinois leadership roles

September 5, 2023

The Cancer Center at Illinois (CCIL) is reshaping its core leadership team, including three transitions in leadership positions by IGB members.

These changes reflect the institute’s continued evolution and build upon its history of research and education excellence. The new positions also underscore the CCIL’s strong commitment to leadership development and the growth of some of the institute’s most visionary members. Each new appointee contributed significantly to CCIL research, education, and outreach initiatives.


September 5, 2023


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First test of anti-cancer agent PAC-1 in human clinical trials shows promise

December 22, 2022

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with neuroendocrine cancers and reduced tumor size in two of those patients. It also showed some therapeutic activity against sarcomas, scientists and clinicians report in the British Journal of Cancer.


December 22, 2022


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Immunotherapy Trials Show Promise for Treating Canine Melanoma

August 9, 2022

Dr. Timothy Fan (ACPP), veterinary oncologist and professor at the University of Illinois College of Veterinary Medicine and a Program Leader for the Cancer Center at Illinois, is leading two clinical trials using similar immunotherapies to treat dogs with malignant melanoma. The novel approaches, developed in partnership with cancer researchers based in Boston, have yielded encouraging results in canine patients, and human trials using the same therapeutic platforms are expected to begin in 2023.


August 9, 2022


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SHIELD program a model for effective pandemic management, data show

June 13, 2022

In the fall of 2020, the University of Illinois Urbana-Champaign welcomed students back for in-person instruction amid the powerful first wave of the COVID-19 pandemic. The university successfully maintained operations throughout the semester – with zero COVID-19-related deaths or hospitalizations in the campus community – thanks to its “SHIELD: Target, Test, Tell” program.


June 13, 2022


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15 Years of IGB: SHIELDing the Illinois community against COVID-19

May 11, 2022

During the earliest months of 2020, COVID-19 seemed like an innocuous event that was too geographically distant to affect the Illinois community. In fact, by March 10th there were only 19 confirmed cases. Nevertheless, Nigel Goldenfeld (BCXT leader/GNDP), former Swanlund Endowed Chair and professor of physics, and Sergei Maslov (BCXT/CABBI), a professor of bioengineering and Bliss Faculty Scholar, were worried. The news from China and Italy was concerning and in four days a significant portion of students, faculty, and staff were going to leave for spring break.


May 11, 2022


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