While the mechanisms driving activation of the innate immune response during viral infection are well understood, the spatial organization remains poorly defined. Using in vitro models of the respiratory tract, we aim to dissect how spatial structure shapes the activation of the innate immune response during influenza A virus infection.
Axioscan image of human bronchial epithelial cells (HBECs). Stained with DAPI (blue) and Phalloidin (green)
Joel Rivera Cardona from the Brooke Lab