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Mining for anti-infectious Molecules from Genomes

The Mining for anti-infectious Molecules from Genomes theme identifies undiscovered microbial sources with medical potential for new antibiotics and other beneficial drugs and investigates the use of antibody-based strategies against avian influenza.

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The research team included (from left) Postdoctoral Researcher Yujie Yuan, Professor of Chemical and Biomolecular Engineering Huimin Zhao, PhD student Wesley Harrison, Postdoctoral Researcher Zhengyi Zhang, and Postdoctoral Researcher Maolin Li (not pictured)
The proposed viral testing method will be developed for fast, easy and affordable use by healthcare providers at community testing centers.
Stephen Long, Stanley O. Ikenberry Endowed Chair Emeritus (deceased)
Illinois researcher Diwaker Shukla shows how deep learning and large-scale computer simulations can help lead the search for safe synthetic cannabinoid-based pharmaceuticals. Photo by Fred Zwicky
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In human breast cancer cells treated with the preclinical drug ErSO (shown), or with doxorubicin, the cellular protein FGD3 causes another protein, calreticulin (in red on the right), to display on the cancer cell surface, attracting and activating immune cells. Micrographs by Junyao Zhu