Nantao Li

The pivotal role of microRNA in diagnosing and monitoring cancer is well known by today’s researchers. “There have been a lot of studies in recent years linking the presence and concentration of specific microRNA sequences to clinical outcomes for people with advanced prostate cancer,” said Brian Cunningham (CGD leader/MMG), a professor of electrical and computer engineering and a program leader at the Cancer Center at Illinois.

As health and research institutions continue to rapidly develop new methodologies for detecting SARS-CoV-2, researchers have found themselves at both forefronts of discovery and featured on the cover of the Journal of the American Chemical Society with their paper "Label-free Digital Detection of Intact Virions by Enhanced Scattering Microscopy."

Current medical diagnostics involve sending samples to laboratory facilities, which can be difficult and expensive. Researchers at the University of Illinois Urbana-Champaign have designed a desk-sized instrument that can make the same measurements at the location where the samples are collected.

A fast, low-cost technique to see and count viruses or proteins from a sample in real time, without any chemicals or dyes, could underpin a new class of devices for rapid diagnostics and viral load monitoring, including HIV and the virus that causes COVID-19.

Researchers at Illinois described the technique, called Photonic Resonator Interferometric Scattering Microscopy, or PRISM, in the journal Nature Communications.

As the numbers of those infected with COVID-19 has continued to climb, the desperate need for a vaccine was apparent. Even now with the invention and administration of several COVID-19 vaccinations, the question remains: How effective are these vaccines?