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Illinois IGB

Saurabh Sinha

How SNPs can be used to detect disease pathways

September 27, 2021

Researchers at the University of Illinois Urbana-Champaign have developed a new computational tool that can identify pathways related to diseases, including breast and prostate cancer, using single-nucleotide polymorphisms. SNPs, which refer to mutations in a person’s DNA, are the most common type of genetic variation among people. The researchers hope that the tool can help them discover new pathways that have been previously overlooked.


September 27, 2021


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New computational models to understand colon cancer

March 29, 2021

Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study, published in Genome Biology, researchers at the University of Illinois Urbana-Champaign have developed a new modeling approach to better understand how tumors become aggressive.


March 29, 2021


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Nelson awarded $4.5M to study prevention, treatment of breast cancer

October 30, 2020

Professor of Molecular and Integrative Physiology Erik Nelson (ACPP) has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP). This prestigious award supports individuals early in their careers who have demonstrated significant potential to effect meaningful change in breast cancer research. Recipients of the Era of Hope Scholar Award are leaders and visionaries in their respective field who go beyond conventional thinking to change the current landscape of breast cancer research and therapy.


October 30, 2020


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Integration of gene regulatory networks in understanding animal behavior

August 7, 2020

For years, scientists have attributed animal behavior to the coordinated activities of neuronal cells and its circuits of neurons, known as the neuronal network (NN). However, researchers are pushing the boundaries in understanding animal behavior through the integration of gene regulation.


August 7, 2020


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Knowledge Engine is ready to accelerate genomic research

January 31, 2020

Five years ago, a team of computer scientists, biomedical researchers, and bioinformaticians set out to bring the power of collective knowledge to genomic research. Their new publication in PLOS Biology shares the culmination of that effort, an analytical platform that guides researchers through the process of interpreting complex genomic datasets.


January 31, 2020


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Artificial intelligence to run the chemical factories of the future

November 13, 2019

A new proof-of-concept study details how an automated system driven by artificial intelligence can design, build, test and learn complex biochemical pathways to efficiently produce lycopene, a red pigment found in tomatoes and commonly used as a food coloring, opening the door to a wide range of biosynthetic applications, researchers report.  


November 13, 2019


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New IGB research theme takes closer look at protection of genomic data

September 18, 2019

Genomic technologies have the power to transform individual healthcare for the better. But with that power comes responsibility—the responsibility to protect the privacy of the individual and to make ethical choices that respect the rights of communities and populations.


September 18, 2019


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New informatics tool makes the most of genomic data

July 11, 2018

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs. A new computational tool developed through a collaboration between the University of Illinois and Mayo Clinic combines multiple types of genomic information to make stronger predictions about what genomic features are associated with specific drug responses.


July 11, 2018


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