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Javier PJennifer Klunkizarro-Cerda

Researchers determine genetic variants offered protection during Black Death, associated with current autoimmune disorders

December 1, 2022

Infectious diseases are some of the strongest selective pressures in human evolution, selecting for genetic variants that increase resistance to infection. In the face of a pandemic, resistance to the disease undergoes strong positive selection that likely affects the genetic makeup of the population afterward. The Black Death, otherwise known as the Bubonic Plague, remains the most devastating pandemic in recorded history, reducing the European population by 30-50% within a 4-year span (1346-1350) and affecting nearly all of Afro-Eurasia.

December 1, 2022

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