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Faculty

Costas D. Maranas

Costas D. Maranas

Donald B. Broughton Professor, Department of Chemical Engineering
The Pennsylvania State University

Website: http://www.maranasgroup.com/
E-mail: costas@psu.edu 

Dr. Maranas’s group develops and deploys computational framework informed by systems engineering and mathematical optimization to understand, analyze and redesign metabolism and proteins. Research interests include: Computational protein design; enzyme and antibody engineering; design of protein pores for bioseparations; reconstruction, curation and analysis of metabolic networks; computational strain design and synthetic biology; metabolism of photosynthetic organisms; metabolism of obligatory anaerobes; modeling of microbial communities; optimization theory and algorithms.

 
Joshua D. Rabinowitz

Joshua D. Rabinowitz

Professor, Department of Chemistry and Lewis-Sigler Institute for Integrative Genomics 
Princeton University 

Website: https://scholar.princeton.edu/rabinowitz/home
E-mail: joshr@princeton.edu 

Dr. Rabinowitz’s group aims to achieve a quantitative, comprehensive understanding of cellular metabolism. Their motivation for studying metabolism is two-fold. From a basic science perspective, the molecular connections involved in metabolism are the best understood of any major biochemical network. Accordingly, metabolism provides a unique opportunity for quantitative analysis. From a practical perspective, derangements of metabolism are a major cause of disease, and small molecules that inhibit metabolism are the basis of many important pharmaceuticals. Accordingly, systems-level analysis of metabolism is likely to yield discoveries of medical significance. 

 

Chris Rao

Christopher V. Rao

Professor, Department of Chemical and Biomolecular Engineering
University of Illinois at Urbana-Champaign

Website: https://raogroupuiuc.github.io/webpage/
E-mail: cvrao@illinois.edu 

Dr. Rao’s group studies how cells process information. His group is especially interested in understanding how decision-making processes are encoded within individual cells through feedback control. Rao group is also engineering bacteria and yeast for the production of biofuels. Specifically, their goal is to optimize the uptake and metabolism of C5/C6 sugars in bacteria by developing new genetic tools. 

 

Martin Wuhr

Martin Wühr

Assistant Professor, Molecular Biology and Lewis-Sigler Institute for Integrative Genomics 
Princeton University

Website: https://scholar.princeton.edu/wuehr
E-mail: wuhr@princeton.edu 

Dr. Wühr’s group aims to elucidate principles by which molecules self-organize into much larger organelles and cells. Specifically, his group studies how proteins partition between nucleus and cytoplasm and how different nuclear composition affects cellular function. To address these questions, his group develops and employs quantitative proteomics in combination with computational, biochemical and imaging approaches.

 

Yasuo Yoshikuni

Yasuo Yoshikuni

Biologist Staff Scientist
DOE Joint Genome Institute (JGI) 

Website: https://jgi.doe.gov/our-science/scientists-jgi/synthetic-biology-pathwa…
E-mail: yyoshikuni@lbl.gov 

Dr. Yoshikuni’s research focus is to discover novel secondary metabolites and to study their roles in microbial-microbial and plant-microbial communications in various environments. He is currently developing design principles, tools, and methodologies to mine and characterize novel secondary metabolite biosynthetic pathways and component enzymes by leveraging on the DOE JGI’s unique resources and capabilities. 

 

Huimin Zhao

Huimin Zhao

Steven L. Miller Chair Professor, Department of Chemical and Biomolecular Engineering 
University of Illinois at Urbana-Champaign 

Website: http://faculty.scs.illinois.edu/~zhaogrp/index.html
E-mail: zhao5@illinois.edu 

Dr. Zhao’s laboratory develops and applies synthetic biology approaches, particularly directed evolution, to engineer functionally improved or novel proteins, pathways, and genomes. In parallel, Zhao laboratory investigates the protein structure-function relationship, cell metabolism, and mechanisms of gene expression and regulation. Zhao group’s current research program centers on four distinct yet related areas, including foundational tool development, drug discovery and development, industrial biotechnology, and mammalian synthetic biology. 

 

Researchers 

 

Ipek Tasan 
Program Manager 
University of Illinois at Urbana-Champaign 
tasan2@illinois.edu 

HoangDinh 
Graduate Student  
The Pennsylvania State University, Maranas Group 
hvd5034@psu.edu 

Patrick Suthers 
Postdoctoral Researcher  
The Pennsylvania State University, Maranas Group 
suthers@engr.psu.edu 

Jack Hu 
Graduate Student  
The Pennsylvania State University, Maranas Group 
m.jack.hu@gmail.com 

Yihui Shen 
Postdoctoral Researcher 
Princeton University, Rabinowitz Group 
yihuis@princeton.edu  

Tianxia Xiao 
Graduate Student 
Princeton University, Rabinowitz Group 
tianxiax@exchange.princeton.edu 

Xi Xing 
Postdoctoral Researcher 
Princeton University, Rabinowitz Group 
xxing@exchange.princeton.edu 

Anshu Deewan 
Graduate Student 
University of Illinois at Urbana-Champaign, Rao Group 
deewan2@illinois.edu 

Donovan Cassidy-Nolan 
Undergraduate Student 
Princeton University, Wühr Group 
dlc4@princeton.edu 

Meera Gupta 
Graduate Student 
Princeton University, Wühr Group 
meerag@princeton.edu 

Chirag Kumar 
Undergraduate Student 
Princeton University, Wühr Group 
ckkumar@princeton.edu 

Lillia Ryazanova 
Research Specialist and Lab Manager  
Princeton University, Wühr Group 
ryazanov@princeton.edu 

Ping-Hung Hsieh
Postdoctoral Researcher 
Joint Genome Institute, Yoshikuni Group 
phhsieh@lbl.gov 

Jing Ke 
Engineer 
Joint Genome Institute, Yoshikuni Group 
jingke@lbl.gov 

Yusuke Sasaki 
Postdoctoral Researcher 
Joint Genome Institute, Yoshikuni Group 
yusukesasaki@lbl.gov 

Zong-Yen Wu 
Postdoctoral Researcher 
Joint Genome Institute, Yoshikuni Group 
zwu@lbl.gov 

Zia Fatma 
Postdoctoral Researcher 
University of Illinois at Urbana-Champaign, Zhao Group 
ziafatma@illinois.edu 

Shekhar Mishra 
Graduate Student
University of Illinois at Urbana-Champaign, Zhao Group
smishr10@illinois.edu 

Carl Schultz 
Graduate Student 
University of Illinois at Urbana-Champaign, Zhao Group 
jcschul2@illinois.edu