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Possible genetic basis and mouse model found for severe nonalcoholic fatty liver disease

February 11, 2023

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found. Mice and human liver cells lacking the SRSF1 gene show all the hallmarks of nonalcoholic steatohepatitis, also known as NASH, the researchers found.


February 11, 2023


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Treatment of liver metastases in breast cancer patients improved by low-carb diets

March 28, 2022

A new study by Zeynep Madak-Erdogan (CGD/EIRH/GSP) Associate Professor of Food Science and Human Nutrition and Cancer Center at Illinois Education Program Leader, and her team have found a new mechanism of endocrine resistance in breast cancers metastasized to the liver.


March 28, 2022


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Exploring RNA Splicing’s Role in Liver Cancer

August 19, 2021

When Auinash Kalsotra (CGD/GNDP), member of the Cancer Center at Illinois, Associate Professor and the William C. Rose Scholar of Biochemistry, attended college at Birla Institute of Technology and Science in India, he knew he wanted to pursue an entrepreneurial career inspired by his family members. Instead of following a traditional business route, Kalsotra’s enterprising genes have led him down a trailblazing scientific journey – uncovering intricacies of cell biological mechanisms that may lead to more targeted and improved cancer therapies.


August 19, 2021


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Division of labor within regenerating liver maintains metabolism, mouse study finds

February 27, 2021

The liver has a rare superpower among body organs – the ability to regenerate, even if 70% of its mass is removed. It also keeps up its metabolic and toxin-removing work during the process of regeneration, thanks to a subset of cells that expand their workload while the rest focus on multiplication, a new study in mice found.


February 27, 2021


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Gene biomarkers indicate liver toxicity quickly and accurately

December 18, 2020

When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal studies.

A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a few days while maintaining a high level of accuracy.


December 18, 2020


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Scientists uncover mechanism that propels liver dev. after birth

November 5, 2015

Any expectant mother will tell you that she wants her baby's organs to develop properly in the womb.

What she may not realize, however, is that a child's internal organs continue to develop for months and years after birth. This critical period is full of cellular changes that transform the organization and function of most tissues. But the exact mechanisms underlying postnatal organ maturation are still a mystery.


November 5, 2015


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