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Antibiotics

Jump ARCHES grant awarded to study antibiotic resistance

April 21, 2022

Established in 2014, the Jump Applied Research in Community Health through Engineering and Simulation (ARCHES) is an endowment partnership between Jump Simulation and Education Center at OSF HealthCare and the Grainger College of Engineering. The grant is awarded to help engineers and physicians combat problems in health care.


April 21, 2022


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Mining microbial genomes to discover natural products

April 11, 2022

The world around us contains many chemicals that are useful for medicines, crop protection, and animal health. These chemicals—known as natural products—have typically been discovered by sheer luck. Unsurprisingly, traditional techniques often find the same products, like antibiotics, repeatedly thus creating a need for new technologies. To address this growing demand, William Metcalf (MMG leader), a professor of microbiology, co-founded the company MicroMGx in 2015.


April 11, 2022


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Unusual biosynthetic pathway offers a key to future natural product discovery

September 10, 2018

Bacteria are master engineers of small, biologically useful molecules. A new study in Nature Communications (DOI: 10.1038/s41467-018-06083-7) has revealed one of the tricks of this microbial trade: synthesizing and then later inserting a nitrogen-nitrogen bond, like a prefabricated part, into a larger molecule.


September 10, 2018


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Researchers Look to HIV Drug To Potentially Fight Bacterial Infections

March 4, 2015

With antibiotic resistance on the rise, scientists are looking for innovative ways to combat bacterial infections. The pathogen that causes conditions from strep throat to flesh-eating disease is among them, but scientists have now found a tool that could help them fight it: a drug approved to treat HIV. Their work, appearing in the journal ACS Chemical Biology, could someday lead to new treatments.


March 4, 2015


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