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William Metcalf

Genome mining reveals novel production pathway for promising malaria treatment

September 4, 2019

Microbes are well-known among biologists as master engineers of useful small molecules, and there are many tricks of their trade. When researchers at the University of Illinois took a closer look at how a known microbe makes a known so-called natural product, they were rewarded with the discovery of a completely unknown biochemical trick.


September 4, 2019


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Researchers discover unique property of critical methane-producing enzyme

September 20, 2017

An unexpected discovery has given scientists a greater understanding of an important methane-producing enzyme.

A team of IGB researchers published a paper in eLife that outlined their findings on an enzyme called methyl-coenzyme M reductase, or MCR.

Their findings overturn what was previously believed to be true in the field: that a set of unique modifications present in MCR were essential to how the enzyme functions.


September 20, 2017


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