Long-term estrogen therapy changes microbial activity in the gut, study finds June 19, 2018 Long-term therapy with estrogen and bazedoxifene alters the microbial composition and activity in the gut, affecting how estrogen is metabolized, a new study in mice found. June 19, 2018 Tags Tags estrogen Xiaoji Liu Colleen Bushell Zeynep Madak-Erdogan Becca Smith Michael Welge Michael Miller John Katzenellenbogen. Related Articles