Team deciphers how myotonic dystrophy generates lethal heart dysfunctions
Roughly 80% of people with myotonic dystrophy – a common form of muscular dystrophy – experience dangerous heart ailments, and heart rhythm defects are the second-leading cause of death in those with the condition. In a new study, researchers traced the molecular events that lead to heart abnormalities in myotonic dystrophy and recreated the disease in a mouse model.
They report their findings in the journal Developmental Cell.