A section of mouse liver stained for ESRP2 and membrane-specific (CTNNB1) marker in a wildtype mouse. Inset: Timed activation of the ESRP2–miR-122 axis promotes hepatocyte binucleation and is linked with promoting hepatocyte quiescence.
Data taken on the LSM 900. Image provided by the Kalsotra Lab associated with this paper https://doi.org/10.1101/gad.352129.124