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Exploring RNA Splicing’s Role in Liver Cancer

August 19, 2021

When Auinash Kalsotra (CGD/GNDP), member of the Cancer Center at Illinois, Associate Professor and the William C. Rose Scholar of Biochemistry, attended college at Birla Institute of Technology and Science in India, he knew he wanted to pursue an entrepreneurial career inspired by his family members. Instead of following a traditional business route, Kalsotra’s enterprising genes have led him down a trailblazing scientific journey – uncovering intricacies of cell biological mechanisms that may lead to more targeted and improved cancer therapies.


August 19, 2021


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New approach eradicates breast cancer in mice

July 21, 2021

A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

Led by scientists at the University of Illinois Urbana-Champaign, the research team reports the findings in the journal Science Translational Medicine.


July 21, 2021


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Cholesterol metabolite induces production of cancer-promoting vesicles

June 9, 2021

Scientists working to understand the cellular processes linking high cholesterol to breast cancer recurrence and metastasis report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are packaged in membrane-bound compartments called extracellular vesicles.


June 9, 2021


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New computational models to understand colon cancer

March 29, 2021

Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study, published in Genome Biology, researchers at the University of Illinois Urbana-Champaign have developed a new modeling approach to better understand how tumors become aggressive.


March 29, 2021


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Leading New Directions in Cancer Research: The Unanswered Black Box

March 11, 2021

Hyunjoon Kong (M-CELS leader/EIRH/RBTE), Robert W. Schafer professor of chemical and biomolecular engineering, approaches cancer research from a perspective that integrates cell engineering and biomaterials. The Kong research team has been working with Georgia Tech University and Massachusetts Institute of Technology (MIT) over the past 10 years under the National Science Foundation (NSF) Science and Technology Center Grant.


March 11, 2021


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Advances in Brain Cancer Research Leads to $3M NCI Award

February 25, 2021

Several Cancer Center at Illinois (CCIL) and IGB members are joining forces with scientists from the Mayo Clinic and Georgetown University on an expansive project targeting improved treatment for glioblastoma (GBM), the most aggressive form of brain cancer. The team, led by Brendan Harley (RBTE leader/EIRH), professor of chemical and biomolecular engineering, recently received a $3M grant from the National Cancer Institute (NCI) for their research which will unite the cell biology, bioengineering, and chemistry behind cancer drug development.


February 25, 2021


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Cancer compound leads to major licensing deal

October 6, 2020

Researchers affiliated with the Cancer Center at Illinois and the IGB discovered a novel small molecule compound that is now the subject of a new global licensing agreement between the pharmaceutical company Bayer AG and the cancer drug development company Systems Oncology LLC. Systems Oncology originally licensed the IP related to the compound in 2018, and this new deal will now give Bayer the exclusive rights to develop the compound, currently called ERSO, as a cancer therapy.


October 6, 2020


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