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John Katzenellenbogen

New compounds block master regulator of cancer growth, metastasis

January 3, 2020

Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and in mouse models of several types of human breast cancer.

The researchers report their findings in the journal NPJ Breast Cancer.


January 3, 2020


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Fatty acids rewire cells to promote obesity-related breast cancer

March 13, 2019

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women’s elevated risk of developing breast cancer after menopause.


March 13, 2019


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