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Breast Cancer

Drugs reprogram genes in breast tumors to prevent endocrine resistance

April 23, 2019

Treating breast tumors with two cancer drugs simultaneously may prevent endocrine resistance by attacking the disease along two separate gene pathways, scientists at the University of Illinois found in a new study.

The two drugs used in the study, selinexor and 4-OHT, caused the cancer cells to die and tumors to regress for prolonged periods, said food science and human nutrition professor Zeynep Madak-Erdogan (ONC-PM), the principal investigator on the study.


April 23, 2019


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Fatty acids rewire cells to promote obesity-related breast cancer

March 13, 2019

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women’s elevated risk of developing breast cancer after menopause.


March 13, 2019


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Cholesterol byproduct hijacks immune cells, lets breast cancer spread

October 13, 2017

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so that they facilitate the cancer's spread instead of stopping it.


October 13, 2017


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