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Anticancer Discovery from Pets to People

The Anticancer Discovery from Pets to People theme provides successful anticancer therapies in dogs and cats that translate to clinical trials in human subjects.

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Erik Nelson (left) and Postdoctoral researcher Natalia Krawczynska
In human breast cancer cells treated with the preclinical drug ErSO (shown), or with doxorubicin, the cellular protein FGD3 causes another protein, calreticulin (in red on the right), to display on the cancer cell surface, attracting and activating immune cells. Micrographs by Junyao Zhu
U. of I. chemistry professor Paul Hergenrother and his colleagues developed a class of antibiotic agents that target pathogenic gram-negative bacteria without harming beneficial microbes. The new compounds are being licensed for further testing and development. Photo by Michelle Hassel
Veterinary clinical medicine professor Dr. Timothy Fan consults Sara Tondini about her dog, Milton. Photo by Fred Zwicky
A new gene editing tool helps cells skip gene regions with problematic mutations. From left, graduate student Shraddha Shirguppe, Professor Pablo Perez-Pinera, and graduate student Angelo Miskalis led a team that applied the tool to reduce proteins associated with Alzheimer’s disease in mice. / Fred Zwicky
A newly established partnership between the OSF Healthcare Cancer Institute in Peoria, IL and the Cancer Center at Illinois, called Breakthrough and Advanced Treatment of (BEAT) Cancer Initiative, facilitates collaboration to improve cancer diagnostics, treatment, and prevention. Dr. Timothy Fan, fourth from left, is shown here at the BEAT Cancer kickoff, hosted by the College of Veterinary Medicine.